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HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 [ Puma concolor (puma) ]

Gene ID: 112871979, updated on 15-Mar-2024

Summary

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Gene symbol
HMGCS2
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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See HMGCS2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020338243.1 (103218448..103235061, complement)

NW_020338243.1Genomic Context describing neighboring genes Neighboring gene 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase Neighboring gene phosphoglycerate dehydrogenase Neighboring gene regenerating family member 4 Neighboring gene 60S ribosomal protein L23a pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020338243 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020338243.1 Reference PumCon1.0 Primary Assembly

    Range
    103218448..103235061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025935105.1 → XP_025790890.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A6P6IRJ9
    Conserved Domains (1) summary
    cl27874
    Location:50 → 464
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

  2. XM_025935104.1 → XP_025790889.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A6P6ISW0
    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
Nucleotide Protein
Heading Accession and Version

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