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NOS1 nitric oxide synthase 1 [ Puma concolor (puma) ]

Gene ID: 112870473, updated on 15-Mar-2024

Summary

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Gene symbol
NOS1
Gene description
nitric oxide synthase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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See NOS1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020340053.1 (16187425..16271669)

NW_020340053.1Genomic Context describing neighboring genes Neighboring gene replication factor C subunit 5 Neighboring gene kinase suppressor of ras 2 Neighboring gene U2 spliceosomal RNA Neighboring gene F-box protein 21 Neighboring gene tescalcin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020340053 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nitric oxide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nitric oxide synthase, brain

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020340053.1 Reference PumCon1.0 Primary Assembly

    Range
    16187425..16271669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025933618.1 → XP_025789403.1  nitric oxide synthase, brain

    UniProtKB/TrEMBL
    A0A6P6IR91
    Conserved Domains (4) summary
    cd06202
    Location:1030 → 1433
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    cd00795
    Location:300 → 711
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:15 → 98
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00258
    Location:757 → 964
    Flavodoxin_1
Nucleotide Protein
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