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CRKL CRK like proto-oncogene, adaptor protein [ Puma concolor (puma) ]

Gene ID: 112870314, updated on 15-Mar-2024

Summary

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Gene symbol
CRKL
Gene description
CRK like proto-oncogene, adaptor protein
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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See CRKL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020340053.1 (1052193..1087042)

NW_020340053.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene serpin family D member 1 Neighboring gene synaptosome associated protein 29 Neighboring gene apoptosis-inducing factor 3-like Neighboring gene apoptosis-inducing factor 3-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020340053 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
crk-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020340053.1 Reference PumCon1.0 Primary Assembly

    Range
    1052193..1087042
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025933459.1 → XP_025789244.1  crk-like protein

    UniProtKB/TrEMBL
    A0A6P6IN13
    Conserved Domains (3) summary
    cd09926
    Location:6 → 106
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:126 → 180
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:237 → 293
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
Nucleotide Protein
Heading Accession and Version

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