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ALS2 alsin Rho guanine nucleotide exchange factor ALS2 [ Puma concolor (puma) ]

Gene ID: 112868570, updated on 15-Mar-2024

Summary

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Gene symbol
ALS2
Gene description
alsin Rho guanine nucleotide exchange factor ALS2
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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See ALS2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
33
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020338243.1 (189362457..189419322, complement)

NW_020338243.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 237 Neighboring gene U6 spliceosomal RNA Neighboring gene MAGUK p55 scaffold protein 4 Neighboring gene U6 spliceosomal RNA Neighboring gene cyclin dependent kinase 15

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020338243 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alsin
Names
ALS2, alsin Rho guanine nucleotide exchange factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020338243.1 Reference PumCon1.0 Primary Assembly

    Range
    189362457..189419322 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025931543.1 → XP_025787328.1  alsin

    UniProtKB/TrEMBL
    A0A6P6IK41
    Conserved Domains (6) summary
    cd13269
    Location:898 → 1003
    PH_alsin; Alsin Pleckstrin homology (PH) domain
    pfam00415
    Location:520 → 567
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam02204
    Location:1547 → 1646
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
    cl02571
    Location:688 → 872
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cl27415
    Location:1041 → 1205
    COG4642; Uncharacterized conserved protein [Function unknown]
    cl27697
    Location:30 → 259
    RCC1; Regulator of chromosome condensation (RCC1) repeat
Nucleotide Protein
Heading Accession and Version

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