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ACAN aggrecan [ Puma concolor (puma) ]

Gene ID: 112855466, updated on 15-Mar-2024

Summary

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Gene symbol
ACAN
Gene description
aggrecan
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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See ACAN in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020339215.1 (10289133..10325678, complement)

NW_020339215.1Genomic Context describing neighboring genes Neighboring gene milk fat globule EGF and factor V/VIII domain containing Neighboring gene hyaluronan and proteoglycan link protein 3 Neighboring gene interferon stimulated exonuclease gene 20 Neighboring gene apoptosis enhancing nuclease

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020339215 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
aggrecan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020339215.1 Reference PumCon1.0 Primary Assembly

    Range
    10289133..10325678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025919130.1 → XP_025774915.1  aggrecan core protein

    UniProtKB/TrEMBL
    A0A6P6HGJ6
    Conserved Domains (6) summary
    cd05900
    Location:43 → 154
    Ig_Aggrecan; Immunoglobulin (Ig)-like domain of the chondroitin sulfate proteoglycan core protein (CSPG), aggrecan
    cd00054
    Location:1532 → 1568
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:153 → 247
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:254 → 349
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    cl02432
    Location:1574 → 1650
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl25496
    Location:1212 → 1527
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
Nucleotide Protein
Heading Accession and Version

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