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MASP1 MBL associated serine protease 1 [ Puma concolor (puma) ]

Gene ID: 112849568, updated on 15-Mar-2024

Summary

Gene symbol
MASP1
Gene description
MBL associated serine protease 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
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Genomic context

See MASP1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020338336.1 (81659947..81714535)

NW_020338336.1Genomic Context describing neighboring genes Neighboring gene somatostatin Neighboring gene receptor transporter protein 4 Neighboring gene receptor transporter protein 1 Neighboring gene ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Genomic regions, transcripts, and products

Genomic Sequence:
NW_020338336 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
mannan-binding lectin serine protease 1
Names
mannan binding lectin serine peptidase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020338336.1 Reference PumCon1.0 Primary Assembly

    Range
    81659947..81714535
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025913228.1XP_025769013.1  mannan-binding lectin serine protease 1

    UniProtKB/TrEMBL
    A0A6P6H0A3
    Conserved Domains (6) summary
    cd00033
    Location:369434
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00041
    Location:30139
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:451696
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00431
    Location:187296
    CUB; CUB domain
    pfam00084
    Location:303364
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:155183
    FXa_inhibition; Coagulation Factor Xa inhibitory site