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MASP2 MBL associated serine protease 2 [ Puma concolor (puma) ]

Gene ID: 112848901, updated on 15-Mar-2024

Summary

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Gene symbol
MASP2
Gene description
MBL associated serine protease 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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See MASP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020338243.1 (7804062..7825379, complement)

NW_020338243.1Genomic Context describing neighboring genes Neighboring gene castor zinc finger 1 Neighboring gene TAR DNA binding protein Neighboring gene exosome component 10 Neighboring gene spermidine synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020338243 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation, lectin pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 2
Names
mannan binding lectin serine peptidase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020338243.1 Reference PumCon1.0 Primary Assembly

    Range
    7804062..7825379 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025912711.1 → XP_025768496.1  mannan-binding lectin serine protease 2

    UniProtKB/TrEMBL
    A0A6P6GZC2
    Conserved Domains (5) summary
    smart00042
    Location:42 → 212
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    smart00179
    Location:259 → 297
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:301 → 412
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:595 → 832
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:450 → 511
    Sushi; Sushi repeat (SCR repeat)
Nucleotide Protein
Heading Accession and Version

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