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CAPN3 calpain 3 [ Canis lupus dingo (dingo) ]

Gene ID: 112676067, updated on 15-Mar-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
See related
Ensembl:ENSCAFG00020004296
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: 30
Exon count:
25
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 30 NC_064272.1 (9495892..9550782)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 30 Unlocalized Scaffold NW_023365227.1 (9450209..9505649)

Chromosome 30 - NC_064272.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 87A Neighboring gene U6 spliceosomal RNA Neighboring gene glucosidase alpha, neutral C Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC118352953 Neighboring gene zinc finger protein 106 Neighboring gene synaptosome associated protein 23

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064272.1 Reference ASM325472v2

    Range
    9495892..9550782
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025473072.3 → XP_025328857.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A8I3P4F7
    Conserved Domains (5) summary
    pfam00648
    Location:77 → 415
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:436 → 579
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:583 → 653
    Calpain_u2; Unstructured region on Calpain-3
    cd15897
    Location:653 → 681
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:653 → 813
    EFh_PEF; The penta-EF hand (PEF) family

  2. XM_025473075.3 → XP_025328860.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NXM8, A0A8I3P4F7
    Conserved Domains (4) summary
    pfam00648
    Location:77 → 415
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:436 → 579
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:583 → 653
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:653 → 821
    EFh_PEF_CAPN3; Calcium-activated neutral

  3. XM_025473076.3 → XP_025328861.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A8I3P4F7
    Conserved Domains (5) summary
    pfam00648
    Location:77 → 415
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:436 → 579
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:583 → 653
    Calpain_u2; Unstructured region on Calpain-3
    cd15897
    Location:653 → 681
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:653 → 813
    EFh_PEF; The penta-EF hand (PEF) family

  4. XM_025473077.3 → XP_025328862.1  calpain-3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0RP42, A0A8I3P4F7
    Conserved Domains (4) summary
    pfam00648
    Location:77 → 415
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:436 → 579
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:583 → 647
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:647 → 815
    EFh_PEF_CAPN3; Calcium-activated neutral

  5. XM_025473081.3 → XP_025328866.1  calpain-3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0NT96, A0A8C0P9U1
    Conserved Domains (3) summary
    pfam00648
    Location:77 → 367
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:388 → 531
    Calpain_III; Calpain large subunit, domain III
    cd16190
    Location:561 → 729
    EFh_PEF_CAPN3; Calcium-activated neutral

RNA

  1. XR_003146267.3 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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