U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PKM pyruvate kinase M1/2 [ Canis lupus dingo (dingo) ]

Gene ID: 112675646, updated on 10-Oct-2024

Summary

Go to the top of the page Help
Gene symbol
PKM
Gene description
pyruvate kinase M1/2
See related
Ensembl:ENSCAFG00020006531
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PKM in Genome Data Viewer
Location:
chromosome: 30
Exon count:
14
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 30 NC_064272.1 (35955347..35981987, complement)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 30 Unlocalized Scaffold NW_023365227.1 (35896425..35922863, complement)

Chromosome 30 - NC_064272.1Genomic Context describing neighboring genes Neighboring gene myosin IXA Neighboring gene U6 spliceosomal RNA Neighboring gene SUMO peptidase family member, NEDD8 specific Neighboring gene GRAM domain containing 2A Neighboring gene uncharacterized LOC125754075 Neighboring gene uncharacterized LOC112675647 Neighboring gene uncharacterized LOC112675642 Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene CUGBP Elav-like family member 6

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
pyruvate kinase PKM

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064272.1 Reference ASM325472v2

    Range
    35955347..35981987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025472272.3 → XP_025328057.1  pyruvate kinase PKM isoform X3

    UniProtKB/TrEMBL
    A0A8C0K2I9, A0A8I3PG67, A0A8I3PMV2, A0A8P0T2E7, A0A8P0T6S6
    Related
    ENSCAFP00020008074.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  2. XM_035708941.2 → XP_035564834.1  pyruvate kinase PKM isoform X4

    UniProtKB/TrEMBL
    A0A8C0STC4, A0A8I3PFA9, A0A8P0NJ34
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  3. XM_025472270.3 → XP_025328055.1  pyruvate kinase PKM isoform X2

    UniProtKB/TrEMBL
    A0A8C0YZD9
    Conserved Domains (1) summary
    cd00288
    Location:102 → 590
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  4. XM_025472271.3 → XP_025328056.1  pyruvate kinase PKM isoform X1

    UniProtKB/TrEMBL
    A0A8C0YZD9
    Conserved Domains (1) summary
    cd00288
    Location:102 → 590
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  5. XM_025472273.3 → XP_025328058.3  pyruvate kinase PKM isoform X5

    UniProtKB/TrEMBL
    A0A8C0SS39, A0A8I3PXE4
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.