U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TJP2 tight junction protein 2 [ Canis lupus dingo (dingo) ]

Gene ID: 112644752, updated on 6-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
TJP2
Gene description
tight junction protein 2
See related
Ensembl:ENSCAFG00020026597
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See TJP2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
30
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 1 NC_064243.1 (88258439..88382473, complement)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 1 Unlocalized Scaffold NW_023365038.1 (88763915..88888768, complement)

Chromosome 1 - NC_064243.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene DPH3 homolog Neighboring gene uncharacterized LOC112644756 Neighboring gene uncharacterized LOC112644754 Neighboring gene 60S ribosomal protein L7a-like Neighboring gene uncharacterized LOC125752256 Neighboring gene frataxin Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene uncharacterized LOC112644762

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064243.1 Reference ASM325472v2

    Range
    88258439..88382473 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025423369.3 → XP_025279154.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NNL3
    Conserved Domains (5) summary
    cd12027
    Location:584 → 646
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:680 → 859
    GuKc; Guanylate kinase homologues
    smart00228
    Location:284 → 365
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 266
    RSRP; Arginine/Serine-Rich protein 1

  2. XM_049092228.1 → XP_048948185.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NNL3

  3. XM_025423367.3 → XP_025279152.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NNL3
    Conserved Domains (5) summary
    cd12027
    Location:584 → 646
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:680 → 859
    GuKc; Guanylate kinase homologues
    smart00228
    Location:284 → 365
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 266
    RSRP; Arginine/Serine-Rich protein 1

  4. XM_049092245.1 → XP_048948202.1  tight junction protein ZO-2 isoform X10

    UniProtKB/TrEMBL
    A0A8I3MNX3

  5. XM_049092239.1 → XP_048948196.1  tight junction protein ZO-2 isoform X7

    UniProtKB/TrEMBL
    A0A8C0NNL3

  6. XM_049092220.1 → XP_048948177.1  tight junction protein ZO-2 isoform X4

    UniProtKB/TrEMBL
    A0A8I3MNX3

  7. XM_049092219.1 → XP_048948176.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0NNL3

  8. XM_049092218.1 → XP_048948175.1  tight junction protein ZO-2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LT93, A0A8I3MNX3

  9. XM_035702316.2 → XP_035558209.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NNL3
    Conserved Domains (5) summary
    cd12027
    Location:584 → 646
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:680 → 859
    GuKc; Guanylate kinase homologues
    smart00228
    Location:284 → 365
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 266
    RSRP; Arginine/Serine-Rich protein 1

  10. XM_049092246.1 → XP_048948203.1  tight junction protein ZO-2 isoform X11

    UniProtKB/TrEMBL
    A0A8C0NF12

  11. XM_035702354.2 → XP_035558247.1  tight junction protein ZO-2 isoform X9

    UniProtKB/TrEMBL
    A0A8C0NF12
    Conserved Domains (5) summary
    cd12027
    Location:607 → 669
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:703 → 882
    GuKc; Guanylate kinase homologues
    smart00228
    Location:307 → 388
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:148 → 289
    RSRP; Arginine/Serine-Rich protein 1

  12. XM_025423365.3 → XP_025279150.1  tight junction protein ZO-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0NF12
    Conserved Domains (5) summary
    cd12027
    Location:607 → 669
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:703 → 882
    GuKc; Guanylate kinase homologues
    smart00228
    Location:307 → 388
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:148 → 291
    RSRP; Arginine/Serine-Rich protein 1

  13. XM_035702347.2 → XP_035558240.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NNL3
    Conserved Domains (5) summary
    cd12027
    Location:584 → 646
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:680 → 859
    GuKc; Guanylate kinase homologues
    smart00228
    Location:284 → 365
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 266
    RSRP; Arginine/Serine-Rich protein 1

  14. XM_025423368.3 → XP_025279153.1  tight junction protein ZO-2 isoform X8

    UniProtKB/TrEMBL
    A0A8I3MEQ4, A0A8P0P9M7
    Conserved Domains (5) summary
    cd12027
    Location:611 → 673
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:707 → 886
    GuKc; Guanylate kinase homologues
    smart00228
    Location:311 → 392
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:152 → 295
    RSRP; Arginine/Serine-Rich protein 1

  15. XM_025423364.3 → XP_025279149.1  tight junction protein ZO-2 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MEQ4, A0A8P0P9M7
    Conserved Domains (5) summary
    cd12027
    Location:611 → 673
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:707 → 886
    GuKc; Guanylate kinase homologues
    smart00228
    Location:311 → 392
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:152 → 295
    RSRP; Arginine/Serine-Rich protein 1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.