U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [ Canis lupus dingo (dingo) ]

Gene ID: 112643241, updated on 6-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
PIK3C2B
Gene description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
See related
Ensembl:ENSCAFG00020006011
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PIK3C2B in Genome Data Viewer
Location:
chromosome: 38
Exon count:
36
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 38 NC_064280.1 (1457976..1523699, complement)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 38 Unlocalized Scaffold NW_023365272.1 (2177637..2243360, complement)

Chromosome 38 - NC_064280.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing A6 Neighboring gene uncharacterized LOC112643244 Neighboring gene protein phosphatase 1 regulatory subunit 15B Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene transfer RNA lysine (anticodon UUU)

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064280.1 Reference ASM325472v2

    Range
    1457976..1523699 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025421155.3 → XP_025276940.3  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0QWC8

  2. XM_025421157.3 → XP_025276942.3  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0QWC8

  3. XM_025421156.3 → XP_025276941.3  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0JYN7, A0A8C0QWC8

  4. XM_025421160.3 → XP_025276945.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A8C0JZU6
    Conserved Domains (6) summary
    cd00895
    Location:646 → 999
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1028 → 1136
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:281 → 453
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1164 → 1286
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:472 → 640
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:23 → 125
    PI3K_rbd; PI3-kinase family, ras-binding domain

  5. XM_025421159.3 → XP_025276944.2  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0JZU6
    Conserved Domains (7) summary
    cd00895
    Location:765 → 1118
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1147 → 1255
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:400 → 572
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1283 → 1405
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    PRK14086
    Location:3 → 89
    dnaA; chromosomal replication initiator protein DnaA
    cd00869
    Location:591 → 759
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:142 → 244
    PI3K_rbd; PI3-kinase family, ras-binding domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.