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PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial [ Theropithecus gelada (gelada) ]

Gene ID: 112629230, updated on 15-Mar-2024

Summary

Gene symbol
PCK2
Gene description
phosphoenolpyruvate carboxykinase 2, mitochondrial
See related
Ensembl:ENSTGEG00000021336
Gene type
protein coding
RefSeq status
MODEL
Organism
Theropithecus gelada
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Theropithecus
Orthologs
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Genomic context

See PCK2 in Genome Data Viewer
Location:
chromosome: 7b
Exon count:
11
Annotation release Status Assembly Chr Location
100 current Tgel_1.0 (GCF_003255815.1) 7b NC_037675.1 (25423436..25433464)

Chromosome 7b - NC_037675.1Genomic Context describing neighboring genes Neighboring gene capping protein regulator and myosin 1 linker 3 Neighboring gene copine 6 Neighboring gene neural retina leucine zipper Neighboring gene DDB1 and CUL4 associated factor 11 Neighboring gene fat storage inducing transmembrane protein 1

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037675.1 Chromosome 7b Reference Tgel_1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphoenolpyruvate carboxykinase [GTP], mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Theropithecus gelada Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tgel_1.0 Primary Assembly

Genomic

  1. NC_037675.1 Reference Tgel_1.0 Primary Assembly

    Range
    25423436..25433464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025392732.1XP_025248517.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8D2FU18
    Related
    ENSTGEP00000026502.1, ENSTGET00000031553.1
    Conserved Domains (1) summary
    cd00819
    Location:1499
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
  2. XM_025392731.1XP_025248516.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8D2FXK6
    Related
    ENSTGEP00000026494.1, ENSTGET00000031546.1
    Conserved Domains (1) summary
    cd00819
    Location:44633
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
  3. XM_025392733.1XP_025248518.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X4

    Conserved Domains (1) summary
    cd00819
    Location:44490
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
  4. XM_025392730.1XP_025248515.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1

    Conserved Domains (1) summary
    cd00819
    Location:97686
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...