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CAPN3 calpain 3 [ Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise) ]

Gene ID: 112391183, updated on 15-Mar-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Neophocaena asiaeorientalis asiaeorientalis (sub-species: asiaeorientalis)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Phocoenidae; Neophocaena
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
100 current Neophocaena_asiaeorientalis_V1 (GCF_003031525.1) Unplaced Scaffold NW_020175821.1 (1683852..1732284, complement)

NW_020175821.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 57 Neighboring gene synaptosome associated protein 23 Neighboring gene zinc finger protein 106 Neighboring gene U2 spliceosomal RNA Neighboring gene glucosidase alpha, neutral C Neighboring gene transmembrane protein 87A Neighboring gene COP9 signalosome complex subunit 7a pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020175821 Unplaced Scaffold Reference Neophocaena_asiaeorientalis_V1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neophocaena asiaeorientalis asiaeorientalis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Neophocaena_asiaeorientalis_V1 Primary Assembly

Genomic

  1. NW_020175821.1 Reference Neophocaena_asiaeorientalis_V1 Primary Assembly

    Range
    1683852..1732284 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024732429.1 → XP_024588197.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A341AGE0
    Conserved Domains (3) summary
    pfam00648
    Location:75 → 367
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:388 → 531
    Calpain_III; Calpain large subunit, domain III
    cd16190
    Location:561 → 729
    EFh_PEF_CAPN3; Calcium-activated neutral

  2. XM_024732434.1 → XP_024588202.1  calpain-3 isoform X5

    UniProtKB/TrEMBL
    A0A341AGE5
    Conserved Domains (3) summary
    pfam00648
    Location:51 → 347
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:368 → 511
    Calpain_III; Calpain large subunit, domain III
    cd16190
    Location:541 → 709
    EFh_PEF_CAPN3; Calcium-activated neutral

  3. XM_024732433.1 → XP_024588201.1  calpain-3 isoform X4

    UniProtKB/TrEMBL
    A0A341ABY2
    Conserved Domains (4) summary
    pfam00648
    Location:75 → 367
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:388 → 531
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:535 → 605
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:605 → 773
    EFh_PEF_CAPN3; Calcium-activated neutral

  4. XM_024732431.1 → XP_024588199.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A341AE75
    Conserved Domains (2) summary
    pfam00648
    Location:75 → 367
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:388 → 526
    Calpain_III; Calpain large subunit, domain III

  5. XM_024732432.1 → XP_024588200.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A341AC34
    Conserved Domains (2) summary
    pfam00648
    Location:75 → 367
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:388 → 462
    Calpain_III; Calpain large subunit, domain III
Nucleotide Protein
Heading Accession and Version

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