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DGKA diacylglycerol kinase alpha [ Desmodus rotundus (common vampire bat) ]

Gene ID: 112319075, updated on 18-Sep-2024

Summary

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Gene symbol
DGKA
Gene description
diacylglycerol kinase alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Desmodus rotundus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Desmodontinae; Desmodus
Orthologs
human mouse all
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Genomic context

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See DGKA in Genome Data Viewer
Location:
chromosome: 3
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2023_02 current HLdesRot8A (GCF_022682495.1) 3 NC_071389.1 (148741722..148764858, complement)
101 previous assembly ASM294091v2 (GCF_002940915.1) Unplaced Scaffold NW_020093622.1 (14806847..14830337, complement)

Chromosome 3 - NC_071389.1Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 2 Neighboring gene premelanosome protein Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene uncharacterized LOC123478276 Neighboring gene matrix metallopeptidase 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022682495.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HLdesRot8A Primary Assembly

Genomic

  1. NC_071389.1 Reference HLdesRot8A Primary Assembly

    Range
    148741722..148764858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045184654.2 → XP_045040589.1  diacylglycerol kinase alpha isoform X2

    Conserved Domains (6) summary
    smart00045
    Location:519 → 700
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:377 → 498
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:4 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20799
    Location:200 → 260
    C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
    cd20890
    Location:269 → 330
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins

  2. XM_024576305.3 → XP_024432073.1  diacylglycerol kinase alpha isoform X2

    Conserved Domains (6) summary
    smart00045
    Location:519 → 700
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:377 → 498
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:4 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20799
    Location:200 → 260
    C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
    cd20890
    Location:269 → 330
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins

  3. XM_024576304.3 → XP_024432072.1  diacylglycerol kinase alpha isoform X1

    Conserved Domains (5) summary
    smart00045
    Location:569 → 750
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:427 → 548
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:163 → 232
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:255 → 303
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam14513
    Location:56 → 159
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  4. XM_045184655.2 → XP_045040590.1  diacylglycerol kinase alpha isoform X2

    Conserved Domains (6) summary
    smart00045
    Location:519 → 700
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:377 → 498
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:4 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20799
    Location:200 → 260
    C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
    cd20890
    Location:269 → 330
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins

  5. XM_053921354.1 → XP_053777329.1  diacylglycerol kinase alpha isoform X3

Nucleotide Protein
Heading Accession and Version

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