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HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 [ Desmodus rotundus (common vampire bat) ]

Gene ID: 112297497, updated on 30-Mar-2024

Summary

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Gene symbol
HSD11B1
Gene description
hydroxysteroid 11-beta dehydrogenase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Desmodus rotundus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Desmodontinae; Desmodus
Orthologs
human mouse all
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Genomic context

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See HSD11B1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_02 current HLdesRot8A (GCF_022682495.1) 12 NC_071398.1 (83439739..83492537)
101 previous assembly ASM294091v2 (GCF_002940915.1) Unplaced Scaffold NW_020090379.1 (2298634..2329102)

Chromosome 12 - NC_071398.1Genomic Context describing neighboring genes Neighboring gene laminin subunit beta 3 Neighboring gene G0/G1 switch 2 Neighboring gene U4 spliceosomal RNA Neighboring gene TRAF3 interacting protein 3 Neighboring gene chromosome 12 C1orf74 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 11-beta-hydroxysteroid dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in steroid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
11-beta-hydroxysteroid dehydrogenase 1
Names
Putative corticosteroid 11-beta-dehydrogenase isozyme 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022682495.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HLdesRot8A Primary Assembly

Genomic

  1. NC_071398.1 Reference HLdesRot8A Primary Assembly

    Range
    83439739..83492537
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_053915212.1 → XP_053771187.1  11-beta-hydroxysteroid dehydrogenase 1

    UniProtKB/TrEMBL
    K9IZK2

  2. XM_024552270.3 → XP_024408038.1  11-beta-hydroxysteroid dehydrogenase 1

    UniProtKB/TrEMBL
    K9IZK2
    Conserved Domains (1) summary
    cd05332
    Location:32 → 279
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs
Nucleotide Protein
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