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mlh3 mutL homolog 3 (E. coli) [ Oryzias melastigma (Indian medaka) ]

Gene ID: 112142194, updated on 10-Jul-2024

Summary

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Gene symbol
mlh3
Gene description
mutL homolog 3 (E. coli)
See related
EnsemblRapid:ENSOMEG00005017038
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryzias melastigma
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
Orthologs
human zebrafish all
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Genomic context

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See mlh3 in Genome Data Viewer
Location:
chromosome: LG22
Exon count:
12
Annotation release Status Assembly LG Location
101 current ASM292280v2 (GCF_002922805.2) LG22 NC_050533.1 (14173365..14179562)
100 previous assembly Om_v0.7.RACA (GCF_002922805.1) Unplaced Scaffold NW_020096073.1 (14173344..14179562)

Linkage Group LG22 - NC_050533.1Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase Nek9 Neighboring gene acylphosphatase 1, erythrocyte (common) type Neighboring gene uncharacterized LOC118598001 Neighboring gene v-fos FBJ murine osteosarcoma viral oncogene homolog Aa Neighboring gene Jun dimerization protein 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tissue-specific transcriptome assemblies of the marine medaka Oryzias melastigma and comparative analysis with the freshwater medaka Oryzias latipes. Lai KP, et al. BMC Genomics, 2015 Feb 27. PMID 25765076, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of mismatch repair complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA mismatch repair protein Mlh3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oryzias melastigma Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM292280v2 Primary Assembly

Genomic

  1. NC_050533.1 Reference ASM292280v2 Primary Assembly

    Range
    14173365..14179562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024265476.2 → XP_024121244.1  DNA mismatch repair protein Mlh3 isoform X1

    UniProtKB/TrEMBL
    A0A834F2F9
    Conserved Domains (3) summary
    smart00853
    Location:902 → 1083
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:206 → 346
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cl28386
    Location:2 → 357
    MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]

  2. XM_024265536.2 → XP_024121304.1  DNA mismatch repair protein Mlh3 isoform X2

    UniProtKB/TrEMBL
    A0A834F2F9
    Conserved Domains (3) summary
    smart00853
    Location:900 → 1081
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:206 → 346
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cl28386
    Location:2 → 357
    MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]

  3. XM_024265611.2 → XP_024121379.1  DNA mismatch repair protein Mlh3 isoform X3

    UniProtKB/TrEMBL
    A0A3B3CN00, A0A834F2F9
    Related
    ENSOMEP00005038825.1, ENSOMET00005043244.1
    Conserved Domains (3) summary
    smart00853
    Location:866 → 1047
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:206 → 346
    MutL_Trans_MLH3; transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain ...
    cl28386
    Location:2 → 357
    MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
Nucleotide Protein Strain
Heading Accession and Version

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