U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC111961646 tight junction protein ZO-2 [ Salvelinus sp. IW2-2015 ]

Gene ID: 111961646, updated on 13-Aug-2024

Summary

Go to the top of the page Help
Gene symbol
LOC111961646
Gene description
tight junction protein ZO-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Salvelinus sp. IW2-2015
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salvelinus
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LOC111961646 in Genome Data Viewer
Location:
chromosome: LG4q.1:29
Exon count:
28
Annotation release Status Assembly LG Location
101 current ASM291031v2 (GCF_002910315.2) LG4q.1:29 NC_036842.1 (21208705..21247993, complement)

Linkage Group LG4q.1:29 - NC_036842.1Genomic Context describing neighboring genes Neighboring gene MAM domain containing 2b Neighboring gene amyloid beta (A4) precursor protein-binding, family A, member 1b Neighboring gene phosphatidylinositol-4-phosphate 5-kinase, type I, beta a Neighboring gene dentin sialophosphoprotein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_036842.1 Chromosome LG4q.1:29 Reference ASM291031v2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Salvelinus alpinus Annotation Release 101

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM291031v2 Primary Assembly

Genomic

  1. NC_036842.1 Reference ASM291031v2 Primary Assembly

    Range
    21208705..21247993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023984067.1 → XP_023839835.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (4) summary
    smart00072
    Location:774 → 952
    GuKc; Guanylate kinase homologues
    cd00992
    Location:60 → 145
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:675 → 740
    SH3; Src Homology 3 domain superfamily
    cl25887
    Location:212 → 340
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  2. XM_023984071.1 → XP_023839839.1  tight junction protein ZO-2 isoform X6

    Conserved Domains (4) summary
    smart00072
    Location:723 → 901
    GuKc; Guanylate kinase homologues
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:624 → 689
    SH3; Src Homology 3 domain superfamily
    cl25887
    Location:161 → 289
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  3. XM_023984070.1 → XP_023839838.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (4) summary
    smart00072
    Location:733 → 911
    GuKc; Guanylate kinase homologues
    cd00992
    Location:19 → 104
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:634 → 699
    SH3; Src Homology 3 domain superfamily
    cl25887
    Location:171 → 299
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  4. XM_023984068.1 → XP_023839836.1  tight junction protein ZO-2 isoform X4

    Conserved Domains (4) summary
    smart00072
    Location:747 → 925
    GuKc; Guanylate kinase homologues
    cd00992
    Location:33 → 118
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:648 → 713
    SH3; Src Homology 3 domain superfamily
    cl25887
    Location:185 → 313
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  5. XM_023984066.1 → XP_023839834.1  tight junction protein ZO-2 isoform X2

    Conserved Domains (4) summary
    smart00072
    Location:793 → 971
    GuKc; Guanylate kinase homologues
    cd00992
    Location:84 → 164
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:694 → 759
    SH3; Src Homology 3 domain superfamily
    cl25887
    Location:231 → 359
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  6. XM_023984065.1 → XP_023839833.1  tight junction protein ZO-2 isoform X1

    Conserved Domains (4) summary
    smart00072
    Location:798 → 976
    GuKc; Guanylate kinase homologues
    cd00992
    Location:84 → 169
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:699 → 764
    SH3; Src Homology 3 domain superfamily
    cl25887
    Location:236 → 364
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  7. XM_023984072.1 → XP_023839840.1  tight junction protein ZO-2 isoform X7

    Conserved Domains (4) summary
    smart00072
    Location:705 → 883
    GuKc; Guanylate kinase homologues
    cd00992
    Location:512 → 589
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:606 → 671
    SH3; Src Homology 3 domain superfamily
    cl25887
    Location:143 → 271
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases