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LOC111258518 E7 enhancer in MEIS1 [ Homo sapiens (human) ]

Gene ID: 111258518, updated on 10-Oct-2023

Summary

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Gene symbol
LOC111258518
Gene description
E7 enhancer in MEIS1
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HCNR602
Summary
This region represents an enhancer located within the MEIS1 gene region. This enhancer drives expression of a reporter transgene in the posterior lateral mesoderm. [provided by RefSeq, Oct 2017]
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Genomic context

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See LOC111258518 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (66521123..66523909)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (66530207..66532993)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (66748255..66751041)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene MEIS1 5' regulatory region Neighboring gene MEIS1 antisense RNA 3 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:66666573-66667772 Neighboring gene HHc2:066588 enhancer in MEIS1 Neighboring gene E2 enhancer in MEIS1 Neighboring gene MEIS1 antisense RNA 2 Neighboring gene E5 enhancer in MEIS1 Neighboring gene Meis homeobox 1 Neighboring gene HHc2:066628 enhancer in MEIS1 Neighboring gene HCNR606 enhancer in MEIS1 Neighboring gene uncharacterized LOC124900511 Neighboring gene HHc2:066650 enhancer in MEIS1 Neighboring gene HCNR617 enhancer in MEIS1 Neighboring gene HHc2:066659 enhancer in MEIS1 Neighboring gene HHc2:067135 enhancer in MEIS1 Neighboring gene HHc2:067347 enhancer downstream of MEIS1 Neighboring gene long intergenic non-protein coding RNA 1798 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:66874822-66875386 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:66875387-66875950

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of MEIS1 by distal enhancer elements in acute leukemia. Wang QF, et al. Leukemia, 2014 Jan. PMID 24022755, Free PMC Article
  2. Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon. Spieler D, et al. Genome Res, 2014 Apr. PMID 24642863, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_055611.1 

    Range
    101..2887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    66521123..66523909
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    66530207..66532993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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