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LOC111240472 Adh1 promoter region [ Mus musculus (house mouse) ]

Gene ID: 111240472, updated on 9-Aug-2024

Summary

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Gene symbol
LOC111240472
Gene description
Adh1 promoter region
Gene type
biological region
Feature type(s)
protein_bind
regulatory: promoter, silencer, transcriptional_cis_regulatory_region
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rr366814
Summary
This region represents the promoter of the alcohol dehydrogenase 1 (class I) (Adh1) gene. This promoter is regulated by binding of CCAAT/enhancer binding protein to recognition sites in this sequence. This region includes a distal promoter element that can function as a silencer of gene expression. [provided by RefSeq, Oct 2017]
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Genomic context

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See LOC111240472 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (137982658..137983465)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (138276897..138277704)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 0610031O16 gene Neighboring gene alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide Neighboring gene predicted gene, 40156 Neighboring gene alcohol dehydrogenase 1 (class I) Neighboring gene predicted gene 16559 Neighboring gene alcohol dehydrogenase 6A (class V)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Protein-DNA interactions in the 5' region of the mouse alcohol dehydrogenase gene Adh-1. Carr LG, et al. Gene, 1989 May 30. PMID 2777084
  2. A novel negative element in the promoter of the mouse alcohol dehydrogenase gene Adh-1. Lin Z, et al. J Biol Chem, 1993 May 15. PMID 8486690
  3. A negative regulatory element upstream from the mouse Adh-1 gene can down-regulate a heterologous promoter. Yu M, et al. Gene, 1994 Apr 20. PMID 8163197
  4. Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development. Vonesch JL, et al. Dev Dyn, 1994 Mar. PMID 8018987
  5. Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity. Zhang K, et al. Gene, 1987. PMID 3428612

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • regulatory region 366814

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_055576.1 

    Range
    101..908
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    137982658..137983465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Research Materials