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MASP2 MBL associated serine protease 2 [ Delphinapterus leucas (beluga whale) ]

Gene ID: 111187114, updated on 15-Mar-2024

Summary

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Gene symbol
MASP2
Gene description
MBL associated serine protease 2
See related
Ensembl:ENSDLEG00000006587
Gene type
protein coding
RefSeq status
MODEL
Organism
Delphinapterus leucas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
Orthologs
human mouse all
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Genomic context

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See MASP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022098043.1 (15258139..15274327)
100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160915.1 (4399128..4418422)

NW_022098043.1Genomic Context describing neighboring genes Neighboring gene exosome component 10 Neighboring gene spermidine synthase Neighboring gene TAR DNA binding protein Neighboring gene chromosome unknown C1orf127 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation, lectin pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 2
Names
mannan binding lectin serine peptidase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228892v3 Primary Assembly

Genomic

  1. NW_022098043.1 Reference ASM228892v3 Primary Assembly

    Range
    15258139..15274327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022598448.2 → XP_022454156.1  mannan-binding lectin serine protease 2 isoform X8

    UniProtKB/TrEMBL
    A0A2Y9QFN1
    Conserved Domains (2) summary
    cd00041
    Location:26 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_022598449.2 → XP_022454157.1  mannan-binding lectin serine protease 2 isoform X8

    UniProtKB/TrEMBL
    A0A2Y9QFN1
    Conserved Domains (2) summary
    cd00041
    Location:26 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_022598450.2 → XP_022454158.1  mannan-binding lectin serine protease 2 isoform X9

    UniProtKB/TrEMBL
    A0A2Y9QFD6
    Conserved Domains (2) summary
    cd00041
    Location:26 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  4. XM_022598440.2 → XP_022454148.1  mannan-binding lectin serine protease 2 isoform X1

    UniProtKB/TrEMBL
    A0A2Y9QFC6
    Related
    ENSDLEP00000009004.1, ENSDLET00000009942.1
    Conserved Domains (4) summary
    cd00041
    Location:185 → 296
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:445 → 682
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:301 → 362
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  5. XM_022598443.2 → XP_022454151.1  mannan-binding lectin serine protease 2 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9Q989
    Conserved Domains (4) summary
    cd00041
    Location:26 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:301 → 362
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  6. XM_022598446.2 → XP_022454154.1  mannan-binding lectin serine protease 2 isoform X6

    UniProtKB/TrEMBL
    A0A2Y9Q508
    Conserved Domains (3) summary
    cd00041
    Location:26 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  7. XM_022598444.2 → XP_022454152.1  mannan-binding lectin serine protease 2 isoform X4

    UniProtKB/TrEMBL
    A0A2Y9QFM7
    Conserved Domains (3) summary
    cd00041
    Location:26 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  8. XM_022598445.2 → XP_022454153.1  mannan-binding lectin serine protease 2 isoform X5

    UniProtKB/TrEMBL
    A0A2Y9QFD1
    Conserved Domains (4) summary
    cd00041
    Location:26 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:301 → 362
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  9. XM_022598447.2 → XP_022454155.1  mannan-binding lectin serine protease 2 isoform X7

    UniProtKB/TrEMBL
    A0A2Y9Q992
    Conserved Domains (3) summary
    cd00041
    Location:26 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  10. XM_022598442.2 → XP_022454150.1  mannan-binding lectin serine protease 2 isoform X2

    UniProtKB/TrEMBL
    A0A2Y9Q987
    Conserved Domains (3) summary
    cd00041
    Location:95 → 206
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:355 → 592
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:211 → 272
    Sushi; Sushi repeat (SCR repeat)
Nucleotide Protein
Heading Accession and Version

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