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DGKA diacylglycerol kinase alpha [ Delphinapterus leucas (beluga whale) ]

Gene ID: 111173895, updated on 18-Sep-2024

Summary

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Gene symbol
DGKA
Gene description
diacylglycerol kinase alpha
See related
Ensembl:ENSDLEG00000006356
Gene type
protein coding
RefSeq status
MODEL
Organism
Delphinapterus leucas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
Orthologs
human mouse all
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Genomic context

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See DGKA in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022098031.1 (21430936..21454534, complement)
100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160865.1 (15368422..15392020, complement)

NW_022098031.1Genomic Context describing neighboring genes Neighboring gene RAB5B, member RAS oncogene family Neighboring gene cyclin dependent kinase 2 Neighboring gene premelanosome protein Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene matrix metallopeptidase 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228892v3 Primary Assembly

Genomic

  1. NW_022098031.1 Reference ASM228892v3 Primary Assembly

    Range
    21430936..21454534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022571902.1 → XP_022427610.1  diacylglycerol kinase alpha isoform X3

    UniProtKB/TrEMBL
    A0A2Y9N0A3
    Conserved Domains (5) summary
    smart00045
    Location:519 → 700
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:377 → 498
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:205 → 253
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam14513
    Location:6 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  2. XM_022571901.1 → XP_022427609.1  diacylglycerol kinase alpha isoform X2

    UniProtKB/TrEMBL
    A0A2Y9MYR3
    Related
    ENSDLEP00000008694.1, ENSDLET00000009600.1
    Conserved Domains (5) summary
    smart00045
    Location:519 → 700
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:377 → 498
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:205 → 253
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam14513
    Location:6 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  3. XM_022571900.1 → XP_022427608.1  diacylglycerol kinase alpha isoform X2

    UniProtKB/TrEMBL
    A0A2Y9MYR3
    Related
    ENSDLEP00000008687.1, ENSDLET00000009592.1
    Conserved Domains (5) summary
    smart00045
    Location:519 → 700
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:377 → 498
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:205 → 253
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam14513
    Location:6 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  4. XM_022571896.1 → XP_022427604.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A2Y9MYR1
    Related
    ENSDLEP00000008713.1, ENSDLET00000009622.1
    Conserved Domains (5) summary
    smart00045
    Location:519 → 700
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:377 → 498
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:205 → 253
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam14513
    Location:6 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  5. XM_022571897.2 → XP_022427605.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A2Y9MYR1
    Conserved Domains (5) summary
    smart00045
    Location:519 → 700
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:377 → 498
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:205 → 253
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam14513
    Location:6 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus
Nucleotide Protein
Heading Accession and Version

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