U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase [ Enhydra lutris kenyoni (northern sea otter) ]

Gene ID: 111154765, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
HMGCL
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase
See related
EnsemblRapid:ENSELKG00000012590
Gene type
protein coding
RefSeq status
MODEL
Organism
Enhydra lutris kenyoni (sub-species: kenyoni)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Lutrinae; Enhydra
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See HMGCL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current ASM228890v2 (GCF_002288905.1) Unplaced Scaffold NW_019154122.1 (2416651..2431890)

NW_019154122.1Genomic Context describing neighboring genes Neighboring gene cannabinoid receptor 2 Neighboring gene alpha-L-fucosidase 1 Neighboring gene UDP-galactose-4-epimerase Neighboring gene lysophospholipase 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_019154122 Unplaced Scaffold Reference ASM228890v2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Enhydra lutris kenyoni Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228890v2 Primary Assembly

Genomic

  1. NW_019154122.1 Reference ASM228890v2 Primary Assembly

    Range
    2416651..2431890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022514657.1 → XP_022370365.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A2Y9KM72
    Related
    ENSELKP00000016700.1, ENSELKT00000018546.1
    Conserved Domains (1) summary
    PLN02746
    Location:17 → 325
    PLN02746; hydroxymethylglutaryl-CoA lyase

  2. XM_022514660.1 → XP_022370368.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A2Y9KB78
    Related
    ENSELKP00000016713.1, ENSELKT00000018560.1
    Conserved Domains (1) summary
    PLN02746
    Location:17 → 254
    PLN02746; hydroxymethylglutaryl-CoA lyase

  3. XM_022514659.1 → XP_022370367.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A2Y9K9I3
    Related
    ENSELKP00000016722.1, ENSELKT00000018571.1
    Conserved Domains (1) summary
    PLN02746
    Location:12 → 318
    PLN02746; hydroxymethylglutaryl-CoA lyase

  4. XM_022514661.1 → XP_022370369.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A2Y9KFW2
    Conserved Domains (1) summary
    cd07938
    Location:1 → 247
    DRE_TIM_HMGL; 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.