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Idd11 insulin dependent diabetes susceptibility 11 [ Mus musculus (house mouse) ]

Gene ID: 110713, updated on 17-Aug-2024

Summary

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Official Symbol
Idd11provided by MGI
Official Full Name
insulin dependent diabetes susceptibility 11provided by MGI
Primary source
MGI:MGI:96402
Gene type
unknown
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus

Genomic context

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Location:
chromosome: 4

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The positional cloning of a type 1 diabetes susceptibility locus, Idd11, located on mouse chromosome 4.
    Title: A recombination hotspot leads to sequence variability within a novel gene (AK005651) and contributes to type 1 diabetes susceptibility.
  2. Idd11 genes on distal chromosome 4 contribute to type 1 diabetes by affecting B cells in NOD mice, potentially by regulating responsiveness to activation and tolerance induction stimuli.
    Title: Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice.
  3. enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic (NOD) mice maps to diabetes susceptibility region Idd11 on chromosome 4
    Title: The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11.
  4. Idd11, a mouse diabetes susceptibility locus, localized to chromosome 4. does not contribute to diabetic abnormalities, which do not need to be corrected to prevent disease.
    Title: Localization of Idd11 is not associated with thymus and nkt cell abnormalities in NOD mice.
Submit: New GeneRIF Correction

Phenotypes

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Associated conditions

Description Tests
insulin dependent diabetes susceptibility 11
GeneReviews: Not available

General gene information

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Property

  • phenotype only

Gene LinkOut

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