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TJP2 tight junction protein 2 [ Numida meleagris (helmeted guineafowl) ]

Gene ID: 110389445, updated on 15-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
Ensembl:ENSNMEG00000011692
Gene type
protein coding
RefSeq status
MODEL
Organism
Numida meleagris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
24
Annotation release Status Assembly Chr Location
100 current NumMel1.0 (GCF_002078875.1) Z NC_034438.1 (34792503..34856131, complement)

Chromosome Z - NC_034438.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxyacyl-CoA dehydratase 4 Neighboring gene interferon kappa-like Neighboring gene uncharacterized LOC110389446 Neighboring gene frataxin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034438.1 Chromosome Z Reference NumMel1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NumMel1.0 Primary Assembly

Genomic

  1. NC_034438.1 Reference NumMel1.0 Primary Assembly

    Range
    34792503..34856131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021379883.1 → XP_021235558.1  tight junction protein ZO-2

    Related
    ENSNMEP00000012671.1, ENSNMET00000019570.1
    Conserved Domains (5) summary
    cd12027
    Location:573 → 635
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:669 → 848
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:145 → 270
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  2. XM_021379882.1 → XP_021235557.1  tight junction protein ZO-2

    Related
    ENSNMEP00000012672.1, ENSNMET00000019571.1
    Conserved Domains (5) summary
    cd12027
    Location:573 → 635
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:669 → 848
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:145 → 270
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version

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