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LOC110386946 Cyp19a1 promoter I.f [ Mus musculus (house mouse) ]

Gene ID: 110386946, updated on 9-Aug-2024

Summary

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Gene symbol
LOC110386946
Gene description
Cyp19a1 promoter I.f
Gene type
biological region
Feature type(s)
protein_bind
regulatory: promoter, transcriptional_cis_regulatory_region
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rr366798
Summary
This region represents an alternate promoter of the Cyp19a1 (cytochrome P450, family 19, subfamily a, polypeptide 1) gene, also known as aromatase. This promoter drives expression in brain regions, and is regulated by estrogen, glucocorticoids, and progesterone. [provided by RefSeq, Jun 2017]
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Genomic context

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See LOC110386946 in Genome Data Viewer
Location:
chromosome: 9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (54136136..54137851)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (54228852..54230567)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene tumor necrosis factor, alpha-induced protein 8-like 3 Neighboring gene STARR-seq mESC enhancer starr_24161 Neighboring gene STARR-seq mESC enhancer starr_24163 Neighboring gene predicted gene, 57545 Neighboring gene cytochrome P450, family 19, subfamily a, polypeptide 1 Neighboring gene predicted gene, 51676 Neighboring gene putative 60S ribosomal protein L37a Neighboring gene gliomedin, opposite strand

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Aromatase promoter I.f is regulated by progesterone receptor in mouse hypothalamic neuronal cell lines. Yilmaz MB, et al. J Mol Endocrinol, 2011 Aug. PMID 21628418, Free PMC Article
  2. Glucocorticoid-induction of hypothalamic aromatase via its brain-specific promoter. Brooks DC, et al. Mol Cell Endocrinol, 2012 Oct 15. PMID 22705581, Free PMC Article
  3. 0.2kb promoter sequence of the murine Cyp19 gene target beta-galactosidase expression to specific brain areas of transgenic mice. Nausch N, et al. J Steroid Biochem Mol Biol, 2007 Feb. PMID 17079138
  4. Characterization and purification of a protein binding to the cis-acting element for brain-specific exon 1 of the mouse aromatase gene. Honda SI, et al. J Steroid Biochem Mol Biol, 2001 Dec. PMID 11850232
  5. Identification of cis-acting elements in the proximal promoter region for brain-specific exon 1 of the mouse aromatase gene. Honda S, et al. Brain Res Mol Brain Res, 1999 Mar 20. PMID 10095084

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • Cyp19a1 brain-specific promoter
  • aromatase promoter I.f
  • regulatory region 366798

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054997.1 

    Range
    101..1816
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    54136136..54137851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version