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Nba2 New Zealand Black autoimmunity 2 [ Mus musculus (house mouse) ]

Gene ID: 110273, updated on 17-Aug-2024

Summary

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Official Symbol
Nba2provided by MGI
Official Full Name
New Zealand Black autoimmunity 2provided by MGI
Primary source
MGI:MGI:1278323
Gene type
unknown
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus

Genomic context

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Location:
chromosome: 1

Bibliography

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Related articles in PubMed

  1. Lupus-prone B6.Nba2 male and female mice display anti-DWEYS reactivity and a neuropsychiatric phenotype. Browne K, et al. Brain Behav Immun, 2021 May. PMID 33607233, Free PMC Article
  2. Genetic dissection of B cell traits in New Zealand black mice. The expanded population of B cells expressing up-regulated costimulatory molecules shows linkage to Nba2. Wither JE, et al. Eur J Immunol, 2000 Feb. PMID 10671190
  3. Limited Effect of Indolamine 2,3-Dioxygenase Expression and Enzymatic Activity on Lupus-Like Disease in B6.Nba2 Mice. Davison LM, et al. Front Immunol, 2019. PMID 31555267, Free PMC Article
  4. Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice. Vyse TJ, et al. J Immunol, 1997 Jun 1. PMID 9164982
  5. Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner. Drake CG, et al. J Immunol, 1995 Mar 1. PMID 7868910

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.
    Title: Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.
  2. The Nba2 locus may play a supplementary role in the pathogenesis of systemic lupus erythematosus by promoting the development of monocytosis and the activation of effector cells bearing stimulatory Fc gamma receptor.
    Title: Contribution of NZB autoimmunity 2 to Y-linked autoimmune acceleration-induced monocytosis in association with murine systemic lupus.
Submit: New GeneRIF Correction

Phenotypes

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Associated conditions

Description Tests
New Zealand Black autoimmunity 2
GeneReviews: Not available

General gene information

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Property

  • phenotype only

Gene LinkOut

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Research Materials