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DEGS2 delta 4-desaturase, sphingolipid 2 [ Phascolarctos cinereus (koala) ]

Gene ID: 110222390, updated on 15-Mar-2024

Summary

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Gene symbol
DEGS2
Gene description
delta 4-desaturase, sphingolipid 2
See related
Ensembl:ENSPCIG00000034681
Gene type
protein coding
RefSeq status
MODEL
Organism
Phascolarctos cinereus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Diprotodontia; Phascolarctidae; Phascolarctos
Orthologs
human mouse all
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Genomic context

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See DEGS2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
100 current phaCin_unsw_v4.1 (GCF_002099425.1) Unplaced Scaffold NW_018344072.1 (2751827..2819047)

NW_018344072.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110222389 Neighboring gene uncharacterized LOC110222391 Neighboring gene uncharacterized LOC110222412 Neighboring gene Enah/Vasp-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018344072 Unplaced Scaffold Reference phaCin_unsw_v4.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingolipid delta-4 desaturase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingosine hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphinganine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phascolarctos cinereus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference phaCin_unsw_v4.1 Primary Assembly

Genomic

  1. NW_018344072.1 Reference phaCin_unsw_v4.1 Primary Assembly

    Range
    2751827..2819047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021007331.1 → XP_020862990.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

    UniProtKB/TrEMBL
    A0A6P5LWR0
    Related
    ENSPCIP00000047944.1, ENSPCIT00000065696.1
    Conserved Domains (2) summary
    cd03508
    Location:26 → 314
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
    pfam08557
    Location:6 → 41
    Lipid_DES; Sphingolipid Delta4-desaturase (DES)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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