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INPP5B inositol polyphosphate-5-phosphatase B [ Phascolarctos cinereus (koala) ]

Gene ID: 110206332, updated on 15-Mar-2024

Summary

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Gene symbol
INPP5B
Gene description
inositol polyphosphate-5-phosphatase B
See related
Ensembl:ENSPCIG00000025724
Gene type
protein coding
RefSeq status
MODEL
Organism
Phascolarctos cinereus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Diprotodontia; Phascolarctidae; Phascolarctos
Orthologs
human mouse all
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Genomic context

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See INPP5B in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current phaCin_unsw_v4.1 (GCF_002099425.1) Unplaced Scaffold NW_018343966.1 (18905943..18977740)

NW_018343966.1Genomic Context describing neighboring genes Neighboring gene four and a half LIM domains 3 Neighboring gene splicing factor 3a subunit 3 Neighboring gene 40S ribosomal protein S19 pseudogene Neighboring gene metal regulatory transcription factor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018343966 Unplaced Scaffold Reference phaCin_unsw_v4.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-1,4,5-trisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
type II inositol 1,4,5-trisphosphate 5-phosphatase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phascolarctos cinereus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference phaCin_unsw_v4.1 Primary Assembly

Genomic

  1. NW_018343966.1 Reference phaCin_unsw_v4.1 Primary Assembly

    Range
    18905943..18977740
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020983617.1 → XP_020839276.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X2

    UniProtKB/TrEMBL
    A0A6P5K349
    Related
    ENSPCIP00000034770.1, ENSPCIT00000042793.2
    Conserved Domains (3) summary
    cd09093
    Location:256 → 549
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:683 → 900
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    pfam16776
    Location:6 → 145
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain

  2. XM_020983618.1 → XP_020839277.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3

    UniProtKB/TrEMBL
    A0A6P5K2Q3
    Conserved Domains (3) summary
    cd09093
    Location:330 → 623
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cl02570
    Location:757 → 832
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    pfam16776
    Location:80 → 219
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain

  3. XM_020983616.1 → XP_020839275.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1

    UniProtKB/TrEMBL
    A0A6P5K2D2
    Related
    ENSPCIP00000034768.2, ENSPCIT00000042791.2
    Conserved Domains (3) summary
    cd09093
    Location:330 → 623
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:757 → 974
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    pfam16776
    Location:80 → 219
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain

  4. XM_020983619.1 → XP_020839278.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X4

    UniProtKB/TrEMBL
    A0A6P5K231
    Related
    ENSPCIP00000034776.1, ENSPCIT00000042799.2
    Conserved Domains (2) summary
    cd09093
    Location:99 → 392
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:526 → 743
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...

  5. XM_020983620.1 → XP_020839279.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X5

    UniProtKB/TrEMBL
    A0A6P5K2I1
    Conserved Domains (2) summary
    cd09093
    Location:45 → 338
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:472 → 689
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
Nucleotide Protein
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