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HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase [ Phascolarctos cinereus (koala) ]

Gene ID: 110206059, updated on 11-Apr-2024

Summary

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Gene symbol
HMGCL
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase
See related
Ensembl:ENSPCIG00000014290
Gene type
protein coding
RefSeq status
MODEL
Organism
Phascolarctos cinereus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Diprotodontia; Phascolarctidae; Phascolarctos
Orthologs
human mouse all
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Genomic context

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See HMGCL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current phaCin_unsw_v4.1 (GCF_002099425.1) Unplaced Scaffold NW_018343966.1 (2387952..2411233, complement)

NW_018343966.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110206062 Neighboring gene lysophospholipase 2 Neighboring gene UDP-galactose-4-epimerase Neighboring gene tissue alpha-L-fucosidase-like Neighboring gene tissue alpha-L-fucosidase-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018343966 Unplaced Scaffold Reference phaCin_unsw_v4.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phascolarctos cinereus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference phaCin_unsw_v4.1 Primary Assembly

Genomic

  1. NW_018343966.1 Reference phaCin_unsw_v4.1 Primary Assembly

    Range
    2387952..2411233 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020983078.1 → XP_020838737.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A6P5K1B1
    Related
    ENSPCIP00000018689.2, ENSPCIT00000023077.2
    Conserved Domains (1) summary
    cd07938
    Location:36 → 294
    DRE_TIM_HMGL; 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain

  2. XM_020983077.1 → XP_020838736.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A6P5K1B6
    Related
    ENSPCIP00000018692.1, ENSPCIT00000023080.2
    Conserved Domains (1) summary
    PLN02746
    Location:10 → 323
    PLN02746; hydroxymethylglutaryl-CoA lyase

  3. XM_020983079.1 → XP_020838738.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A6P5K0L1
    Conserved Domains (1) summary
    PLN02746
    Location:1 → 261
    PLN02746; hydroxymethylglutaryl-CoA lyase
Nucleotide Protein
Heading Accession and Version

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