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PLCB1 phospholipase C beta 1 [ Pogona vitticeps (central bearded dragon) ]

Gene ID: 110087370, updated on 15-Mar-2024

Summary

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Gene symbol
PLCB1
Gene description
phospholipase C beta 1
See related
Ensembl:ENSPVIG00000007252
Gene type
protein coding
RefSeq status
MODEL
Organism
Pogona vitticeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Acrodonta; Agamidae; Amphibolurinae; Pogona
Orthologs
human mouse all
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Genomic context

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See PLCB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
34
Annotation release Status Assembly Chr Location
100 current pvi1.1 (GCF_900067755.1) Unplaced Scaffold NW_018151222.1 (97356..653442)

NW_018151222.1Genomic Context describing neighboring genes Neighboring gene thioredoxin related transmembrane protein 4 Neighboring gene uncharacterized LOC110087371 Neighboring gene 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018151222.1 Unplaced Scaffold Reference pvi1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pogona vitticeps Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference pvi1.1

Genomic

  1. NW_018151222.1 Reference pvi1.1

    Range
    97356..653442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020809018.1 → XP_020664677.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A6J0UVE4
    Related
    ENSPVIP00000009062.1, ENSPVIT00000011558.1
    Conserved Domains (6) summary
    cd00275
    Location:681 → 800
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:319 → 647
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 151
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:907 → 943
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1007 → 1180
    PLC-beta_C; PLC-beta C terminal
    cd16208
    Location:156 → 306
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)

  2. XM_020809019.1 → XP_020664678.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2

    UniProtKB/TrEMBL
    A0A6J0UXL1
    Related
    ENSPVIP00000009057.1, ENSPVIT00000011554.1
    Conserved Domains (6) summary
    cd00275
    Location:681 → 800
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:319 → 647
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 151
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:907 → 943
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1007 → 1145
    PLC-beta_C; PLC-beta C terminal
    cd16208
    Location:156 → 306
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)

  3. XM_020809021.1 → XP_020664680.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

    UniProtKB/TrEMBL
    A0A6J0UZD2
    Conserved Domains (6) summary
    cd00275
    Location:577 → 696
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:215 → 543
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    pfam06631
    Location:803 → 839
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:903 → 1076
    PLC-beta_C; PLC-beta C terminal
    cd16208
    Location:52 → 202
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    cl17171
    Location:1 → 47
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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