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cbl Cbl proto-oncogene [ Oncorhynchus kisutch (coho salmon) ]

Gene ID: 109905383, updated on 14-Dec-2023

Summary

Gene symbol
cbl
Gene description
Cbl proto-oncogene
See related
Ensembl:ENSOKIG00005004818
Gene type
protein coding
RefSeq status
MODEL
Organism
Oncorhynchus kisutch
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
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Genomic context

See cbl in Genome Data Viewer
Location:
chromosome: LG15
Exon count:
16
Annotation release Status Assembly LG Location
101 current Okis_V2 (GCF_002021735.2) LG15 NC_034188.2 (49746457..49811047)
100 previous assembly Okis_V1 (GCF_002021735.1) LG15 NC_034188.1 (32309573..32379846)

Linkage Group LG15 - NC_034188.2Genomic Context describing neighboring genes Neighboring gene glutamate receptor ionotropic, kainate 4-like Neighboring gene U7 small nuclear RNA Neighboring gene dynein regulatory complex subunit 12 homolog Neighboring gene cell surface glycoprotein MUC18 Neighboring gene calmodulin-alpha-like

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
E3 ubiquitin-protein ligase CBL

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oncorhynchus kisutch Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Okis_V2 Primary Assembly

Genomic

  1. NC_034188.2 Reference Okis_V2 Primary Assembly

    Range
    49746457..49811047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020502724.2XP_020358313.1  E3 ubiquitin-protein ligase CBL

    UniProtKB/TrEMBL
    A0A8C7CS50, A0A8C7CSX5
    Related
    ENSOKIP00005010750.1, ENSOKIT00005011441.1
    Conserved Domains (6) summary
    cd09920
    Location:239335
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd14393
    Location:873912
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    pfam02262
    Location:37158
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:162245
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
    cd16709
    Location:345410
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    cl26464
    Location:464711
    Atrophin-1; Atrophin-1 family