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cisha cytokine inducible SH2-containing protein a [ Oncorhynchus kisutch (coho salmon) ]

Gene ID: 109898581, updated on 12-Sep-2024

Summary

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Gene symbol
cisha
Gene description
cytokine inducible SH2-containing protein a
See related
Ensembl:ENSOKIG00005003534
Gene type
protein coding
RefSeq status
MODEL
Organism
Oncorhynchus kisutch
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
Also known as
cish
Orthologs
zebrafish all
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Genomic context

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See cisha in Genome Data Viewer
Location:
chromosome: LG1
Exon count:
4
Annotation release Status Assembly LG Location
101 current Okis_V2 (GCF_002021735.2) LG1 NC_034174.2 (16375916..16381816, complement)
100 previous assembly Okis_V1 (GCF_002021735.1) LG1 NC_034174.1 (55744679..55748263)

Linkage Group LG1 - NC_034174.2Genomic Context describing neighboring genes Neighboring gene GATOR complex protein NPRL2-like Neighboring gene NPR2 like, GATOR1 complex subunit Neighboring gene HemK methyltransferase family member 1 Neighboring gene uncharacterized LOC109898545 Neighboring gene glycerate kinase Neighboring gene T cell leukemia translocation altered

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytokine-inducible SH2-containing protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oncorhynchus kisutch Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Okis_V2 Primary Assembly

Genomic

  1. NC_034174.2 Reference Okis_V2 Primary Assembly

    Range
    16375916..16381816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031786941.1 → XP_031642801.1  cytokine-inducible SH2-containing protein-like isoform X3

    UniProtKB/TrEMBL
    A0A8C7CK81
    Conserved Domains (2) summary
    smart00969
    Location:166 → 199
    SOCS_box; The SOCS box acts as a bridge between specific substrate- binding domains and more generic proteins that comprise a large family of E3 ubiquitin protein ligases
    cd10718
    Location:35 → 122
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)

  2. XM_031786891.1 → XP_031642751.1  cytokine-inducible SH2-containing protein-like isoform X2

    UniProtKB/TrEMBL
    A0A8C7CK81, A0A8C7CR03
    Related
    ENSOKIP00005007840.1, ENSOKIT00005008343.1
    Conserved Domains (2) summary
    smart00969
    Location:188 → 221
    SOCS_box; The SOCS box acts as a bridge between specific substrate- binding domains and more generic proteins that comprise a large family of E3 ubiquitin protein ligases
    cd10718
    Location:57 → 144
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)

  3. XM_031786851.1 → XP_031642711.1  cytokine-inducible SH2-containing protein-like isoform X1

    UniProtKB/TrEMBL
    A0A8C7CK81, A0A8C7CLB2
    Related
    ENSOKIP00005007846.1, ENSOKIT00005008350.1
    Conserved Domains (2) summary
    smart00969
    Location:207 → 240
    SOCS_box; The SOCS box acts as a bridge between specific substrate- binding domains and more generic proteins that comprise a large family of E3 ubiquitin protein ligases
    cd10718
    Location:76 → 163
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
Nucleotide Protein
Heading Accession and Version

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