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Dhx8 DEAH-box helicase 8 [ Castor canadensis (American beaver) ]

Gene ID: 109682457, updated on 14-Mar-2024

Summary

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Gene symbol
Dhx8
Gene description
DEAH-box helicase 8
See related
Ensembl:ENSCCNG00000005583
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See Dhx8 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017870004.1 (2152..22295, complement)

NW_017870004.1Genomic Context describing neighboring genes Neighboring gene ETS translocation variant 4 Neighboring gene ATP-dependent RNA helicase DHX8-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017870004.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De Novo Genome and Transcriptome Assembly of the Canadian Beaver (Castor canadensis). Lok S, et al. G3 (Bethesda), 2017 Feb 9. PMID 28087693, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in spliceosomal complex disassembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular anatomical structure IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent RNA helicase DHX8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017870004.1 Reference C.can genome v1.0

    Range
    2152..22295 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020157692.1 → XP_020013281.1  ATP-dependent RNA helicase DHX8 isoform X1

    UniProtKB/TrEMBL
    A0A250YM96
    Related
    ENSCCNP00000009511.1, ENSCCNT00000012512.1
    Conserved Domains (2) summary
    COG1643
    Location:563 → 1225
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    cd05684
    Location:271 → 349
    S1_DHX8_helicase; The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced mRNA by releasing ...

  2. XM_020157693.1 → XP_020013282.1  ATP-dependent RNA helicase DHX8 isoform X2

    UniProtKB/TrEMBL
    A0A8B7U2A6
    Conserved Domains (2) summary
    COG1643
    Location:282 → 944
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    cd05684
    Location:1 → 68
    S1_DHX8_helicase; The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced mRNA by releasing ...
Nucleotide Protein
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