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Fcr Fc receptor [ Mus musculus (house mouse) ]

Gene ID: 109615, updated on 17-Aug-2024

Summary

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Official Symbol
Fcrprovided by MGI
Official Full Name
Fc receptorprovided by MGI
Primary source
MGI:MGI:95501
Gene type
other
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Annotation information
not in current annotation release
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Genomic context

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Location:
chromosome: 12

Bibliography

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Related articles in PubMed

  1. Antibody against extracellular vaccinia virus (EV) protects mice through complement and Fc receptors. Cohen ME, et al. PLoS One, 2011. PMID 21687676, Free PMC Article
  2. Phosphorylation of SNAP-23 at Ser95 causes a structural alteration and negatively regulates Fc receptor-mediated phagosome formation and maturation in macrophages. Sakurai C, et al. Mol Biol Cell, 2018 Jul 15. PMID 29771640, Free PMC Article
  3. Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy. Wang TT, et al. Cell, 2015 Jul 2. PMID 26140596, Free PMC Article
  4. A Cdc42 activation cycle coordinated by PI 3-kinase during Fc receptor-mediated phagocytosis. Beemiller P, et al. Mol Biol Cell, 2010 Feb 1. PMID 19955216, Free PMC Article
  5. Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens. Moore T, et al. J Infect Dis, 2003 Aug 15. PMID 12898452

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SNAP-23 phosphorylation at Ser95 played an important role in the regulation of SNARE-dependent membrane fusion during FcR-mediated phagocytosis.
    Title: Phosphorylation of SNAP-23 at Ser95 causes a structural alteration and negatively regulates Fc receptor-mediated phagosome formation and maturation in macrophages.
  2. both complement and FcRs are important effector mechanisms for antibody-mediated protection from vaccinia virus challenge
    Title: Antibody against extracellular vaccinia virus (EV) protects mice through complement and Fc receptors.
  3. Data identify a Cdc42 activation cycle in which FcR-activated Cdc42 stimulates PI3K and actin polymerization, and the subsequent increase of 3'PIs in cup membranes inactivates Cdc42 to allow actin recycling necessary for phagosome formation.
    Title: A Cdc42 activation cycle coordinated by PI 3-kinase during Fc receptor-mediated phagocytosis.
  4. FcR(-/-) mice exhibited a delayed and reduced frequency of Chlamydia-specific Th1 cells, compared to FcR(+/+) mice
    Title: Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens.
Submit: New GeneRIF Correction

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