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CD14 CD14 molecule [ Bos indicus (zebu cattle) ]

Gene ID: 109562104, updated on 14-Mar-2024

Summary

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Gene symbol
CD14
Gene description
CD14 molecule
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos indicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See CD14 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
2
Annotation release Status Assembly Chr Location
100 current Bos_indicus_1.0 (GCF_000247795.1) 7 NC_032656.1 (51049605..51052640, complement)

Chromosome 7 - NC_032656.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109562102 Neighboring gene steroid receptor RNA activator 1 Neighboring gene amyloid beta precursor protein binding family B member 3 Neighboring gene solute carrier family 35 member A4 Neighboring gene transmembrane and coiled-coil domains 6 Neighboring gene NADH:ubiquinone oxidoreductase subunit A2 Neighboring gene IK cytokine

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032656.1 Chromosome 7 Reference Bos_indicus_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A preliminary sketch of horn cancer transcriptome in Indian zebu cattle. Tripathi AK, et al. Gene, 2012 Feb 1. PMID 22134011
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables lipopolysaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipopolysaccharide-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type I interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type II interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor 4 signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of lipopolysaccharide receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
monocyte differentiation antigen CD14
Names
monocyte differentiation antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos indicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_indicus_1.0 Primary Assembly

Genomic

  1. NC_032656.1 Reference Bos_indicus_1.0 Primary Assembly

    Range
    51049605..51052640 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019965053.1 → XP_019820612.1  monocyte differentiation antigen CD14 isoform X1

    UniProtKB/TrEMBL
    A0A6P5C661
    Conserved Domains (3) summary
    sd00033
    Location:197 → 224
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:119 → 144
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl26161
    Location:117 → 340
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  2. XM_019965054.1 → XP_019820613.1  monocyte differentiation antigen CD14 isoform X2

    UniProtKB/TrEMBL
    A0A6P5C566
    Conserved Domains (3) summary
    sd00033
    Location:195 → 222
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:117 → 142
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl26161
    Location:115 → 338
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
Nucleotide Protein
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