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PAN2 poly(A) specific ribonuclease subunit PAN2 [ Bos indicus (zebu cattle) ]

Gene ID: 109559360, updated on 14-Mar-2024

Summary

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Gene symbol
PAN2
Gene description
poly(A) specific ribonuclease subunit PAN2
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos indicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PAN2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
26
Annotation release Status Assembly Chr Location
100 current Bos_indicus_1.0 (GCF_000247795.1) 5 NC_032654.1 (61457320..61471285)

Chromosome 5 - NC_032654.1Genomic Context describing neighboring genes Neighboring gene apolipoprotein F-like Neighboring gene signal transducer and activator of transcription 2 Neighboring gene interleukin 23 subunit alpha Neighboring gene uncharacterized LOC109559365 Neighboring gene canopy FGF signaling regulator 2 Neighboring gene citrate synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032654.1 Chromosome 5 Reference Bos_indicus_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables poly(A)-specific ribonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear-transcribed mRNA poly(A) tail shortening IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in P-body IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of PAN complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
PAB-dependent poly(A)-specific ribonuclease subunit PAN2
Names
PAN2 poly(A) specific ribonuclease subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos indicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_indicus_1.0 Primary Assembly

Genomic

  1. NC_032654.1 Reference Bos_indicus_1.0 Primary Assembly

    Range
    61457320..61471285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019961027.1 → XP_019816586.1  PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X3

    UniProtKB/TrEMBL
    A0A6P5BTM9
    Conserved Domains (3) summary
    cd06143
    Location:971 → 1144
    PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
    cd02672
    Location:502 → 917
    Peptidase_C19P; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl25539
    Location:204 → 357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_019961026.1 → XP_019816585.1  PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X2

    UniProtKB/TrEMBL
    A0A6P5BTN4
    Conserved Domains (3) summary
    cd06143
    Location:974 → 1147
    PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
    cd02672
    Location:502 → 920
    Peptidase_C19P; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl25539
    Location:204 → 357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_019961025.1 → XP_019816584.1  PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X1

    UniProtKB/TrEMBL
    A0A6P5BTN0
    Conserved Domains (3) summary
    cd06143
    Location:975 → 1148
    PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
    cd02672
    Location:502 → 921
    Peptidase_C19P; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl25539
    Location:204 → 357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_019961028.1 → XP_019816587.1  PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X4

    UniProtKB/TrEMBL
    A0A6P5BTP0
    Conserved Domains (3) summary
    cd06143
    Location:970 → 1143
    PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
    cd02672
    Location:502 → 916
    Peptidase_C19P; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl25539
    Location:204 → 357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_019961029.1 → XP_019816588.1  PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X5

    UniProtKB/TrEMBL
    A0A6P5BTP1
    Conserved Domains (3) summary
    cd06143
    Location:975 → 1126
    PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
    cd02672
    Location:502 → 921
    Peptidase_C19P; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl25539
    Location:204 → 357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. XM_019961030.1 → XP_019816589.1  PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X6

    UniProtKB/TrEMBL
    A0A6P5BTN3
    Conserved Domains (3) summary
    cd06143
    Location:836 → 1009
    PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
    cd02672
    Location:363 → 782
    Peptidase_C19P; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl25539
    Location:65 → 218
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
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