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PLCE1 phospholipase C epsilon 1 [ Bos indicus (zebu cattle) ]

Gene ID: 109553155, updated on 14-Mar-2024

Summary

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Gene symbol
PLCE1
Gene description
phospholipase C epsilon 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos indicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PLCE1 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
34
Annotation release Status Assembly Chr Location
100 current Bos_indicus_1.0 (GCF_000247795.1) 26 NC_032675.1 (15919461..16330764)

Chromosome 26 - NC_032675.1Genomic Context describing neighboring genes Neighboring gene mitochondrial import inner membrane translocase subunit Tim17-A pseudogene Neighboring gene solute carrier family 35 member G1 Neighboring gene uncharacterized LOC109553245 Neighboring gene NOC3 like DNA replication regulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032675.1 Chromosome 26 Reference Bos_indicus_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos indicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_indicus_1.0 Primary Assembly

Genomic

  1. NC_032675.1 Reference Bos_indicus_1.0 Primary Assembly

    Range
    15919461..16330764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019953110.1 → XP_019808669.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1

    UniProtKB/TrEMBL
    A0A6P5BH55
    Conserved Domains (5) summary
    cd00275
    Location:1864 → 1980
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd01780
    Location:2133 → 2232
    PLC_epsilon_RA; Ubiquitin-like domain of Phosphatidylinositide-specific phospholipase
    cd08596
    Location:1388 → 1829
    PI-PLCc_epsilon; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-epsilon
    pfam00617
    Location:534 → 713
    RasGEF; RasGEF domain
    cd16203
    Location:1194 → 1374
    EFh_PI-PLCepsilon; EF-hand motif found in phosphoinositide phospholipase C epsilon 1 (PI-PLC-epsilon1)

  2. XM_019953111.1 → XP_019808670.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X2

    UniProtKB/TrEMBL
    A0A6P5BGP1
    Conserved Domains (5) summary
    cd00275
    Location:1371 → 1487
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd01780
    Location:1640 → 1739
    PLC_epsilon_RA; Ubiquitin-like domain of Phosphatidylinositide-specific phospholipase
    cd08596
    Location:895 → 1336
    PI-PLCc_epsilon; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-epsilon
    pfam00617
    Location:41 → 220
    RasGEF; RasGEF domain
    cd16203
    Location:701 → 881
    EFh_PI-PLCepsilon; EF-hand motif found in phosphoinositide phospholipase C epsilon 1 (PI-PLC-epsilon1)
Nucleotide Protein
Heading Accession and Version

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