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nfx1 nuclear transcription factor, X-box binding 1 [ Hippocampus comes (tiger tail seahorse) ]

Gene ID: 109521837, updated on 14-Mar-2024

Summary

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Gene symbol
nfx1
Gene description
nuclear transcription factor, X-box binding 1
See related
Ensembl:ENSHCOG00000001235
Gene type
protein coding
RefSeq status
MODEL
Organism
Hippocampus comes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Syngnathiaria; Syngnathiformes; Syngnathoidei; Syngnathidae; Hippocampus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current H_comes_QL1_v1 (GCF_001891065.1) Unplaced Scaffold NW_017805564.1 (62782..72259, complement)

NW_017805564.1Genomic Context describing neighboring genes Neighboring gene chondroitin polymerizing factor 2 Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit D3b Neighboring gene ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b Neighboring gene arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017805564.1 Unplaced Scaffold Reference H_comes_QL1_v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcriptional repressor NF-X1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Hippocampus comes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference H_comes_QL1_v1 Primary Assembly

Genomic

  1. NW_017805564.1 Reference H_comes_QL1_v1 Primary Assembly

    Range
    62782..72259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019879908.1 → XP_019735467.1  transcriptional repressor NF-X1-like

    UniProtKB/TrEMBL
    A0A3Q2XKF4
    Related
    ENSHCOP00000000426.1, ENSHCOT00000013799.1
    Conserved Domains (3) summary
    cd02643
    Location:884 → 957
    R3H_NF-X1; R3H domain of the X1 box binding protein (NF-X1) and related proteins. Human NF-X1 is a transcription factor that regulates the expression of class II major histocompatibility complex (MHC) genes. The Drosophila homolog shuttle craft (STC) has been shown ...
    cd06008
    Location:392 → 440
    NF-X1-zinc-finger; Presumably a zinc binding domain, which has been shown to bind to DNA in the human nuclear transcriptional repressor NF-X1. The zinc finger can be characterized by the pattern C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C. The NF-X1 zinc finger ...
    cd16696
    Location:251 → 305
    RING-CH-C4HC3_NFX1; RING-CH finger, H2 subclass (C4HC3-type), found in transcriptional repressor NF-X1 and similar proteins
Nucleotide Protein
Heading Accession and Version

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