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LOC109279971 VISTA enhancer mm612 [ Mus musculus (house mouse) ]

Gene ID: 109279971, updated on 9-Aug-2024

Summary

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Gene symbol
LOC109279971
Gene description
VISTA enhancer mm612
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mm612; Rr1358
Summary
This genomic region represents an enhancer that was validated by the STARR-seq (self-transcribing active regulatory region sequencing) reporter assay in metastable (SL) mouse embryonic stem cells, where it was defined as a C1 class enhancer that overlaps an active chromatin signature. This locus also includes a conserved genomic element that can function as an enhancer. It can activate a Hsp68 promoter coupled to a LacZ reporter gene in embryonic hindbrain, midbrain, forebrain, limb, branchial arch, eye and nose of transgenic mice. [provided by RefSeq, Jul 2023]
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Genomic context

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See LOC109279971 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (26032735..26036582)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (25543011..25545762)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene 10689 Neighboring gene predicted gene, 31045 Neighboring gene Fgfr1 promoter region Neighboring gene predicted gene, 31288 Neighboring gene fibroblast growth factor receptor 1 Neighboring gene STARR-seq mESC enhancer starr_20978 Neighboring gene predicted gene 16159 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:26686963-26687146 Neighboring gene leucine zipper-EF-hand containing transmembrane protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E8232 Neighboring gene STARR-positive B cell enhancer ABC_E2860

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. VISTA Enhancer Browser--a database of tissue-specific human enhancers. Visel A, et al. Nucleic Acids Res, 2007 Jan. PMID 17130149, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • STARR-seq mESC enhancer starr_20977
  • regulatory region 1358

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054243.2 

    Range
    101..3948
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    26032735..26036582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version