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aptx aprataxin [ Scleropages formosus (Asian bonytongue) ]

Gene ID: 108925927, updated on 14-Mar-2024

Summary

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Gene symbol
aptx
Gene description
aprataxin
See related
Ensembl:ENSSFOG00015009267
Gene type
protein coding
RefSeq status
MODEL
Organism
Scleropages formosus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala; Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages
Orthologs
human zebrafish all
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Genomic context

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See aptx in Genome Data Viewer
Location:
chromosome: 16
Exon count:
8
Annotation release Status Assembly Chr Location
101 current fSclFor1.1 (GCF_900964775.1) 16 NC_041821.1 (14569176..14573528)
100 previous assembly ASM162426v1 (GCF_001624265.1) Unplaced Scaffold NW_017371568.1 (973569..977588)

Chromosome 16 - NC_041821.1Genomic Context describing neighboring genes Neighboring gene glyoxylate reductase/hydroxypyruvate reductase b Neighboring gene SMU1 DNA replication regulator and spliceosomal factor Neighboring gene DnaJ heat shock protein family (Hsp40) member A1 Neighboring gene TBC1 domain family member 2A-like Neighboring gene solute carrier family 44 member 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA 5'-adenosine monophosphate hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-strand break-containing DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in single strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
aprataxin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Scleropages formosus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fSclFor1.1 Primary Assembly

Genomic

  1. NC_041821.1 Reference fSclFor1.1 Primary Assembly

    Range
    14569176..14573528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029258870.1 → XP_029114703.1  aprataxin isoform X3

    UniProtKB/TrEMBL
    A0A0P7V6N7, A0A8C9RA45
    Conserved Domains (3) summary
    TIGR01663
    Location:2 → 106
    PNK-3'Pase; polynucleotide 5'-kinase 3'-phosphatase
    cd01278
    Location:175 → 276
    aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
    pfam16278
    Location:294 → 350
    zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger

  2. XM_018738290.2 → XP_018593806.1  aprataxin isoform X4

    UniProtKB/TrEMBL
    A0A0P7V6N7

  3. XM_018738288.2 → XP_018593804.1  aprataxin isoform X3

    UniProtKB/TrEMBL
    A0A0P7V6N7, A0A8C9RA45
    Conserved Domains (3) summary
    TIGR01663
    Location:2 → 106
    PNK-3'Pase; polynucleotide 5'-kinase 3'-phosphatase
    cd01278
    Location:175 → 276
    aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
    pfam16278
    Location:294 → 350
    zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger

  4. XM_018738291.2 → XP_018593807.1  aprataxin isoform X5

    UniProtKB/TrEMBL
    A0A0P7V6N7

  5. XM_018738286.2 → XP_018593802.1  aprataxin isoform X1

    UniProtKB/TrEMBL
    A0A1W4YQG7

  6. XM_018738287.2 → XP_018593803.1  aprataxin isoform X2

    UniProtKB/TrEMBL
    A0A1W4YZE6

  7. XM_018738289.2 → XP_018593805.1  aprataxin isoform X3

    UniProtKB/TrEMBL
    A0A0P7V6N7, A0A8C9RA45
    Related
    ENSSFOP00015014380.1, ENSSFOT00015014552.2
    Conserved Domains (3) summary
    TIGR01663
    Location:2 → 106
    PNK-3'Pase; polynucleotide 5'-kinase 3'-phosphatase
    cd01278
    Location:175 → 276
    aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
    pfam16278
    Location:294 → 350
    zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger

  8. XM_029258871.1 → XP_029114704.1  aprataxin isoform X6

    Conserved Domains (2) summary
    cd01278
    Location:90 → 191
    aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
    pfam16278
    Location:209 → 265
    zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
Nucleotide Protein
Heading Accession and Version

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