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rasgrp3.L RAS guanyl releasing protein 3 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108716683, updated on 17-Aug-2024

Summary

Official Symbol
rasgrp3.L
Official Full Name
RAS guanyl releasing protein 3 L homeolog
Primary source
Xenbase:XB-GENE-17335177
Locus tag
XELAEV_18026728mg
See related
EnsemblRapid:ENSXLAG00005015513
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
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Genomic context

See rasgrp3.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
17
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (47347918..47404302)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (46168000..46222858)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene latent transforming growth factor beta binding protein 1 L homeolog Neighboring gene uncharacterized protein MGC115675 Neighboring gene protein FAM98A Neighboring gene cysteine rich transmembrane BMP regulator 1 (chordin-like) L homeolog

Genomic regions, transcripts, and products

General protein information

Preferred Names
ras guanyl-releasing protein 3
Names
RAS guanyl releasing protein 3 (calcium and DAG-regulated) L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    47347918..47404302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562723.1XP_041418657.1  ras guanyl-releasing protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8J1KMW1, A0A974CWP2
    Related
    ENSXLAP00005045576.1, ENSXLAT00005046675.1
    Conserved Domains (4) summary
    cd06224
    Location:11126
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00109
    Location:468517
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    cd00051
    Location:398449
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00155
    Location:148369
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
  2. XM_018263021.2XP_018118510.2  ras guanyl-releasing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8J0VFY3, A0A974CWP2
    Related
    ENSXLAP00005045571.1, ENSXLAT00005046671.1
    Conserved Domains (4) summary
    cd06224
    Location:11126
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00109
    Location:494543
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    smart00147
    Location:148384
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    cd00051
    Location:424475
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
  3. XM_041562722.1XP_041418656.1  ras guanyl-releasing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8J1KMW0, A0A974CWP2
    Conserved Domains (4) summary
    cd06224
    Location:11126
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00109
    Location:494543
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    smart00147
    Location:148384
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    cd00051
    Location:424475
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...