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map4k3.L mitogen-activated protein kinase kinase kinase kinase 3 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108716656, updated on 18-Sep-2024

Summary

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Official Symbol
map4k3.L
Official Full Name
mitogen-activated protein kinase kinase kinase kinase 3 L homeolog
Primary source
Xenbase:XB-GENE-6489189
Locus tag
XELAEV_18026669mg
See related
EnsemblRapid:ENSXLAG00005017565
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
glk; mapkkkk3; rab8ipl1
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Genomic context

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See map4k3.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
35
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (42567860..42749040)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (41403320..41584966)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene THUMP domain containing 2 L homeolog Neighboring gene transmembrane protein 178A L homeolog Neighboring gene multiple coagulation factor deficiency protein 2 homolog Neighboring gene fasciculation and elongation protein zeta 2 (zygin II) L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables MAP kinase kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables histone H2AS1 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitogen-activated protein kinase kinase kinase kinase 3
Names
mekkk 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    42567860..42749040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562695.1 → XP_041418629.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A8J1KQX3, A0A974CS17
    Conserved Domains (2) summary
    smart00036
    Location:591 → 904
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06613
    Location:15 → 273
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  2. XM_041562696.1 → XP_041418630.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A8J1KMU1
    Conserved Domains (2) summary
    smart00036
    Location:573 → 886
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06613
    Location:15 → 273
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  3. XM_041562697.1 → XP_041418631.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A8J1KMT4, A0A974CS17
    Related
    ENSXLAP00005051881.1, ENSXLAT00005053043.1
    Conserved Domains (2) summary
    smart00036
    Location:570 → 883
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06613
    Location:15 → 273
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  4. XM_041562699.1 → XP_041418633.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X5

    UniProtKB/TrEMBL
    A0A8J1KPG9
    Conserved Domains (2) summary
    smart00036
    Location:552 → 865
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06613
    Location:15 → 273
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  5. XM_018262947.2 → XP_018118436.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X4

    UniProtKB/TrEMBL
    A0A8J0VAU4, A0A974CS17
    Related
    ENSXLAP00005051926.1, ENSXLAT00005053088.1

  6. XM_018262949.2 → XP_018118438.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X6

    UniProtKB/TrEMBL
    A0A1L8G7I6, A0A974CS17, A0A974CUV5
    Related
    ENSXLAP00005051899.1, ENSXLAT00005053061.1
Nucleotide Protein Strain
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