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b4galnt1.S beta-1,4-N-acetyl-galactosaminyl transferase 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108709867, updated on 4-Nov-2024

Summary

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Official Symbol
b4galnt1.S
Official Full Name
beta-1,4-N-acetyl-galactosaminyl transferase 1 S homeolog
Primary source
Xenbase:XB-GENE-17345437
Locus tag
XELAEV_18015948mg
See related
EnsemblRapid:ENSXLAG00005033896 AllianceGenome:Xenbase:XB-GENE-17345437
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable acetylgalactosaminyltransferase activity. Predicted to act upstream of or within ganglioside biosynthetic process and lipid glycosylation. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 26. Orthologous to human B4GALNT1 (beta-1,4-N-acetyl-galactosaminyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See b4galnt1.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (132894212..132959820, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (123882218..123947504, complement)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene Sp5 transcription factor-like S homeolog Neighboring gene solute carrier family 26 member 10 S homeolog Neighboring gene osteosarcoma amplified 9, endoplasmic reticulum lectin S homeolog Neighboring gene provisional ortholog of core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ganglioside biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
beta-1,4 N-acetylgalactosaminyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    132894212..132959820 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041584433.1 → XP_041440367.1  beta-1,4 N-acetylgalactosaminyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8J1MF74, A0A974HZ74
    Related
    ENSXLAP00005101170.1, ENSXLAT00005103144.1
    Conserved Domains (1) summary
    cd00761
    Location:323 → 415
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  2. XM_018250090.2 → XP_018105579.1  beta-1,4 N-acetylgalactosaminyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A1L8H9W8, A0A974HWE0, A0A974HZ74
    Related
    ENSXLAP00005101213.1, ENSXLAT00005103187.1
    Conserved Domains (1) summary
    pfam00535
    Location:275 → 398
    Glycos_transf_2; Glycosyl transferase family 2

  3. XM_018250091.2 → XP_018105580.1  beta-1,4 N-acetylgalactosaminyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A1L8H9W8, A0A974HWE0, A0A974HZ74
    Conserved Domains (1) summary
    pfam00535
    Location:275 → 398
    Glycos_transf_2; Glycosyl transferase family 2

  4. XM_041584434.1 → XP_041440368.1  beta-1,4 N-acetylgalactosaminyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A1L8H9W8, A0A974HWE0, A0A974HZ74
    Conserved Domains (1) summary
    pfam00535
    Location:275 → 398
    Glycos_transf_2; Glycosyl transferase family 2
Nucleotide Protein Strain
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