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sgcg.L sarcoglycan gamma L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108708720, updated on 4-Nov-2024

Summary

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Official Symbol
sgcg.L
Official Full Name
sarcoglycan gamma L homeolog
Primary source
Xenbase:XB-GENE-6488344
Locus tag
XELAEV_18013783mg
See related
EnsemblRapid:ENSXLAG00005000743 AllianceGenome:Xenbase:XB-GENE-6488344
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to act upstream of or within cardiac muscle tissue development and heart contraction. Predicted to be located in cytoskeleton and sarcolemma. Predicted to be part of sarcoglycan complex. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2C and type 2 diabetes mellitus. Orthologous to human SGCG (sarcoglycan gamma). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sgcg.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (166657305..166777087, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (160757832..160840981, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene tumor necrosis factor receptor superfamily member 19 L homeolog Neighboring gene sacsin molecular chaperone L homeolog Neighboring gene fibroblast growth factor 9 L homeolog Neighboring gene mitochondrial calcium uptake 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within cardiac muscle tissue development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within heart contraction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of sarcoglycan complex IEA
Inferred from Electronic Annotation
more info
  
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
gamma-sarcoglycan

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    166657305..166777087 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041582667.1 → XP_041438601.1  gamma-sarcoglycan isoform X2

    UniProtKB/TrEMBL
    A0A1L8HJ85, A0A974DRY8
    Conserved Domains (1) summary
    pfam04790
    Location:42 → 300
    Sarcoglycan_1; Sarcoglycan complex subunit protein

  2. XM_041582666.1 → XP_041438600.1  gamma-sarcoglycan isoform X1

    UniProtKB/TrEMBL
    A0A8J1MBY8
    Related
    ENSXLAP00005002201.1, ENSXLAT00005002247.1

  3. XM_041582668.1 → XP_041438602.1  gamma-sarcoglycan isoform X3

    UniProtKB/TrEMBL
    A0A8J0UJZ0
    Conserved Domains (1) summary
    pfam04790
    Location:26 → 284
    Sarcoglycan_1; Sarcoglycan complex subunit protein

  4. XM_018247732.2 → XP_018103221.1  gamma-sarcoglycan isoform X3

    UniProtKB/TrEMBL
    A0A8J0UJZ0
    Related
    ENSXLAP00005002199.1, ENSXLAT00005002245.1
    Conserved Domains (1) summary
    pfam04790
    Location:26 → 284
    Sarcoglycan_1; Sarcoglycan complex subunit protein
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases