U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tmtc4.L transmembrane and tetratricopeptide repeat containing 4 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108708472, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
tmtc4.L
Official Full Name
transmembrane and tetratricopeptide repeat containing 4 L homeolog
Primary source
Xenbase:XB-GENE-6488174
Locus tag
XELAEV_18013110mg
See related
EnsemblRapid:ENSXLAG00005000489 AllianceGenome:Xenbase:XB-GENE-6488174
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to act upstream of or within endoplasmic reticulum unfolded protein response and protein O-linked mannosylation. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness. Orthologous to human TMTC4 (transmembrane O-mannosyltransferase targeting cadherins 4). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See tmtc4.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
22
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (125301045..125349121)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (119451699..119499087)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene integrin subunit beta like 1 L homeolog Neighboring gene sodium leak channel, non selective L homeolog Neighboring gene gamma-glutamylamine cyclotransferase L homeolog Neighboring gene propionyl-CoA carboxylase subunit alpha L homeolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables dolichyl-phosphate-mannose-protein mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein O-mannosyl-transferase TMTC4

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    125301045..125349121
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018247225.2 → XP_018102714.1  protein O-mannosyl-transferase TMTC4

    UniProtKB/TrEMBL
    A0A1L8HH43, A0A974DPA4

  2. XM_018247221.2 → XP_018102710.1  protein O-mannosyl-transferase TMTC4

    UniProtKB/TrEMBL
    A0A1L8HH43, A0A974DPA4
    Related
    ENSXLAP00005001364.1, ENSXLAT00005001404.1

  3. XM_018247220.2 → XP_018102709.1  protein O-mannosyl-transferase TMTC4

    UniProtKB/TrEMBL
    A0A1L8HH43, A0A974DPA4
    Related
    ENSXLAP00005001366.1, ENSXLAT00005001406.1

  4. XM_018247224.2 → XP_018102713.1  protein O-mannosyl-transferase TMTC4

    UniProtKB/TrEMBL
    A0A1L8HH43, A0A974DPA4

  5. XM_018247222.2 → XP_018102711.1  protein O-mannosyl-transferase TMTC4

    UniProtKB/TrEMBL
    A0A1L8HH43, A0A974DPA4

  6. XM_018247223.2 → XP_018102712.1  protein O-mannosyl-transferase TMTC4

    UniProtKB/TrEMBL
    A0A1L8HH43, A0A974DPA4
    Related
    ENSXLAP00005001360.1, ENSXLAT00005001400.1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases