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mapkapk5.S mitogen-activated protein kinase-activated protein kinase 5 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108707170, updated on 4-Nov-2024

Summary

Official Symbol
mapkapk5.S
Official Full Name
mitogen-activated protein kinase-activated protein kinase 5 S homeolog
Primary source
Xenbase:XB-GENE-6486595
Locus tag
XELAEV_18010668mg
See related
EnsemblRapid:ENSXLAG00005007578 AllianceGenome:Xenbase:XB-GENE-6486595
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable several functions, including ATP binding activity; calmodulin binding activity; and protein serine/threonine kinase activity. Predicted to act upstream of or within Ras protein signal transduction; negative regulation of TOR signaling; and protein phosphorylation. Predicted to be located in cytoplasm and nucleus. Orthologous to human MAPKAPK5 (MAPK activated protein kinase 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See mapkapk5.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (151661763..151699952)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (135886174..135924979)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene cut like homeobox 2 S homeolog Neighboring gene myosin light chain 2 S homeolog Neighboring gene transmembrane protein 116 S homeolog Neighboring gene endoplasmic reticulum protein 29 S homeolog

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables calcium-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables calcium/calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables mitogen-activated protein kinase binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
MAP kinase-activated protein kinase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    151661763..151699952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018244219.2XP_018099708.1  MAP kinase-activated protein kinase 5 isoform X1

    UniProtKB/TrEMBL
    A0A1L8HQS3, A0A974DWS8
    Related
    ENSXLAP00005021545.1, ENSXLAT00005022236.1
  2. XM_018244220.2XP_018099709.1  MAP kinase-activated protein kinase 5 isoform X2

    UniProtKB/TrEMBL
    A0A8J0UD08
    Related
    ENSXLAP00005021533.1, ENSXLAT00005022224.1