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ube2r2.L ubiquitin conjugating enzyme E2 R2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108705456, updated on 4-Nov-2024

Summary

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Official Symbol
ube2r2.L
Official Full Name
ubiquitin conjugating enzyme E2 R2 L homeolog
Primary source
Xenbase:XB-GENE-17336506
Locus tag
XELAEV_18000140mg
See related
EnsemblRapid:ENSXLAG00005001384 AllianceGenome:Xenbase:XB-GENE-17336506
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ubc3b; cdc34b; e2-cdc34b
Summary
Predicted to enable ATP binding activity and ubiquitin conjugating enzyme activity. Predicted to act upstream of or within protein polyubiquitination and ubiquitin-dependent protein catabolic process. Orthologous to human UBE2R2 (ubiquitin conjugating enzyme E2 R2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ube2r2.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (228686308..228716118)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694904.1 (127087..156885, complement)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene aquaporin 3 (Gill blood group) L homeolog Neighboring gene nucleolar protein 6 L homeolog Neighboring gene DDB1 and CUL4 associated factor 12 L homeolog Neighboring gene small nucleolar RNA SNORD121A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin conjugating enzyme activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ubiquitin-conjugating enzyme E2 R2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    228686308..228716118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018242337.2 → XP_018097826.1  ubiquitin-conjugating enzyme E2 R2

    UniProtKB/TrEMBL
    A0A974BQS2, A0A974DVL6, A0AA97PYK5, A0AAF6DLY2, Q7SZU1
    Related
    ENSXLAP00005004204.1, ENSXLAT00005004270.1
    Conserved Domains (1) summary
    cd00195
    Location:11 → 169
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
Nucleotide Protein Strain
Heading Accession and Version

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