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sorbs1.S sorbin and SH3 domain containing 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108705262, updated on 4-Nov-2024

Summary

Official Symbol
sorbs1.S
Official Full Name
sorbin and SH3 domain containing 1 S homeolog
Primary source
Xenbase:XB-GENE-6487058
Locus tag
XELAEV_18004504mg
See related
EnsemblRapid:ENSXLAG00005034389 AllianceGenome:Xenbase:XB-GENE-6487058
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
flaf2; r85fl; sh3d5; sorb1; sh3p12
Summary
Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human SORBS1 (sorbin and SH3 domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See sorbs1.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
35
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (28798030..28936770)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694875.1 (343374..482012)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene annexin A7 S homeolog Neighboring gene uncharacterized LOC121396264 Neighboring gene PDZ and LIM domain 1 S homeolog Neighboring gene traf2 and NCK-interacting protein kinase-like Neighboring gene helicase, lymphoid specific S homeolog

Genomic regions, transcripts, and products

General protein information

Preferred Names
sorbin and SH3 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    28798030..28936770
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041571065.1XP_041426999.1  sorbin and SH3 domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8J1LDD5
    Conserved Domains (4) summary
    cd11919
    Location:11431197
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:12171274
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:293336
    Sorb; Sorbin homologous domain
    cl17036
    Location:16411698
    SH3; Src Homology 3 domain superfamily
  2. XM_041571063.1XP_041426997.1  sorbin and SH3 domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8J1LBU8
    Conserved Domains (4) summary
    cd11919
    Location:15211575
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:15951652
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:671714
    Sorb; Sorbin homologous domain
    cl17036
    Location:20192076
    SH3; Src Homology 3 domain superfamily
  3. XM_041571064.1XP_041426998.1  sorbin and SH3 domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8J1LBT7
    Conserved Domains (4) summary
    cd11919
    Location:12601314
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:13341391
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:410453
    Sorb; Sorbin homologous domain
    cl17036
    Location:17581815
    SH3; Src Homology 3 domain superfamily
  4. XM_041571068.1XP_041427002.1  sorbin and SH3 domain-containing protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8J1LBV3, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:9831037
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:10571114
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:671714
    Sorb; Sorbin homologous domain
    cl17036
    Location:14811538
    SH3; Src Homology 3 domain superfamily
  5. XM_041571066.1XP_041427000.1  sorbin and SH3 domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8J1LEA2, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:10391093
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:11131170
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:671714
    Sorb; Sorbin homologous domain
    cl17036
    Location:15371594
    SH3; Src Homology 3 domain superfamily
  6. XM_041571067.1XP_041427001.1  sorbin and SH3 domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8J1LBZ7, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:10381092
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:11121169
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:671714
    Sorb; Sorbin homologous domain
    cl17036
    Location:15361593
    SH3; Src Homology 3 domain superfamily
  7. XM_041571069.1XP_041427003.1  sorbin and SH3 domain-containing protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A8J1LBU2, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:9821036
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:10561113
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:671714
    Sorb; Sorbin homologous domain
    cl17036
    Location:14801537
    SH3; Src Homology 3 domain superfamily
  8. XM_041571070.1XP_041427004.1  sorbin and SH3 domain-containing protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A8J1LDE1
    Related
    ENSXLAP00005103038.1, ENSXLAT00005105042.1
    Conserved Domains (4) summary
    cd11919
    Location:10381092
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:11121169
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:671714
    Sorb; Sorbin homologous domain
    cl17036
    Location:12381295
    SH3; Src Homology 3 domain superfamily
  9. XM_041571071.1XP_041427005.1  sorbin and SH3 domain-containing protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A8J1LEA9
    Related
    ENSXLAP00005103257.1, ENSXLAT00005105262.1
    Conserved Domains (4) summary
    cd11919
    Location:10381092
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:11121169
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:671714
    Sorb; Sorbin homologous domain
    cl17036
    Location:12181275
    SH3; Src Homology 3 domain superfamily
  10. XM_041571072.1XP_041427006.1  sorbin and SH3 domain-containing protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A8J1LC02, A0A974CFL7
    Conserved Domains (4) summary
    cd11919
    Location:777831
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:851908
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:410453
    Sorb; Sorbin homologous domain
    cl17036
    Location:12751332
    SH3; Src Homology 3 domain superfamily