slc18a3.S solute carrier family 18 (vesicular acetylcholine transporter), member 3 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: slc18a3.S
Official Full Name: solute carrier family 18 (vesicular acetylcholine transporter), member 3 S homeolog
Primary source: Xenbase:XB-GENE-17337065
Locus tag: XELAEV_18000595mg
See related: EnsemblRapid:ENSXLAG00005018818 AllianceGenome:Xenbase:XB-GENE-17337065
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: VAChT
Summary: Predicted to enable acetylcholine transmembrane transporter activity and xenobiotic transmembrane transporter activity. Predicted to act upstream of or within several processes, including chemical synaptic transmission; serotonin transport; and xenobiotic transport. Predicted to be located in membrane and terminal bouton. Predicted to be part of AP-1 adaptor complex and AP-2 adaptor complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 21. Orthologous to human SLC18A3 (solute carrier family 18 member A3). [provided by Alliance of Genome Resources, Nov 2024]
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Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (43109315..43112596)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	Unplaced Scaffold	NW_016694810.1 (4095312..4098706, complement)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables acetylcholine transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables xenobiotic transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chemical synaptic transmission	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within establishment of localization in cell	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neurotransmitter transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within serotonin transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within xenobiotic transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of AP-1 adaptor complex	IEA Inferred from Electronic Annotation more info
part_of AP-2 adaptor complex	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in terminal bouton	IEA Inferred from Electronic Annotation more info