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fzd7.S frizzled class receptor 7 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108703060, updated on 4-Nov-2024

Summary

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Official Symbol
fzd7.S
Official Full Name
frizzled class receptor 7 S homeolog
Primary source
Xenbase:XB-GENE-17333315
Locus tag
XELAEV_18047362mg
See related
EnsemblRapid:ENSXLAG00005028549 AllianceGenome:Xenbase:XB-GENE-17333315
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
fz7; Fz-7; Xfz7; frz7; frz-7; fz7-b; Fz-7-B; Xfz7-B; fzd7-b; frizzled7; frizzled-7
Summary
Predicted to enable Wnt-protein binding activity and syndecan binding activity. Acts upstream of or within Wnt signaling pathway; convergent extension involved in gastrulation; and dorsal/ventral axis specification. Predicted to be located in endosome membrane and plasma membrane. Orthologous to human FZD7 (frizzled class receptor 7). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See fzd7.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
1
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (78810523..78814847, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (72100888..72105215, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD70 Neighboring gene NOP58 ribonucleoprotein S homeolog Neighboring gene small ubiquitin like modifier 1 S homeolog Neighboring gene ALS2, alsin Rho guanine nucleotide exchange factor S homeolog Neighboring gene uncharacterized LOC121399092

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Xenopus frizzled-7 morphant displays defects in dorsoventral patterning and convergent extension movements during gastrulation. Sumanas S, et al. Genesis, 2001 Jul. PMID 11477687
  2. Two novel Xenopus frizzled genes expressed in developing heart and brain. Wheeler GN, et al. Mech Dev, 1999 Aug. PMID 10446283
  3. Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Wong HC, et al. Mol Cell, 2003 Nov. PMID 14636582, Free PMC Article
  4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables Wnt receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
  
enables Wnt-protein binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables syndecan binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within convergent extension involved in gastrulation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within dorsal/ventral axis specification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mesoderm formation ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein localization ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within tissue morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
frizzled-7-B-like
Names
frizzled 7
frizzled-7-B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    78810523..78814847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018239009.2 → XP_018094498.1  frizzled-7-B-like

    UniProtKB/Swiss-Prot
    Q8AVJ9
    UniProtKB/TrEMBL
    A0A1L8EPZ4, A0A974H1E5
    Related
    ENSXLAP00005084954.1, ENSXLAT00005086616.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8AVJ9.1 GenPept UniProtKB/Swiss-Prot:Q8AVJ9

Gene LinkOut

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Molecular Biology Databases